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Generation of 1E8 Single Chain Fv-Fc Construct Against Human CD59

BACKGROUND: Therapeutic approaches using monoclonal antibodies (mAbs) against complement regulatory proteins (CRPs:i.e.,CD46,CD55 and CD59) have been reported for adjuvant cancer therapy. In this study, we generated a recombinant 1E8 single-chain anti-CD59 antibody (scFv-Fc) and tested anti-cancer e...

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Detalles Bibliográficos
Autores principales:	Hong, Jeong-Won, Cho, Woon-Dong, Hong, Kwon Pyo, Kim, So-Seul, Son, Seung-Myoung, Yun, Seok-Joong, Lee, Ho-Chang, Yoon, Sang-Soon, Song, Hyung-Geun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Association of Immunologists 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329601/ https://www.ncbi.nlm.nih.gov/pubmed/22536168 http://dx.doi.org/10.4110/in.2012.12.1.33

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