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Heterogenecity of fibroblasts

Fibroblasts are a major stromal cell type present in human connective tissue maintaining the structural integrity in health. Depending on the situation, location and various conditions, fibroblasts exhibit considerable variation in morphology, size and shape that suggest the existence of discrete ce...

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Detalles Bibliográficos
Autores principales: Ravikanth, Manyam, Soujanya, P, Manjunath, K, Saraswathi, TR, Ramachandran, CR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329689/
https://www.ncbi.nlm.nih.gov/pubmed/22529592
http://dx.doi.org/10.4103/0973-029X.84516
Descripción
Sumario:Fibroblasts are a major stromal cell type present in human connective tissue maintaining the structural integrity in health. Depending on the situation, location and various conditions, fibroblasts exhibit considerable variation in morphology, size and shape that suggest the existence of discrete cellular subsets. The purpose of this short communication is to provide information regarding the heterogenecity of fibroblasts and its variability in physiological and pathological conditions.