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Estimating Hepatic Glucokinase Activity Using a Simple Model of Lactate Kinetics

OBJECTIVE: Glucokinase (GCK) acts as a component of the “glucose sensor” in pancreatic β-cells and possibly in other tissues, including the brain. However, >99% of GCK in the body is located in the liver, where it serves as a “gatekeeper”, determining the rate of hepatic glucose phosphorylation....

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Detalles Bibliográficos
Autores principales:	Stefanovski, Darko, Youn, Jang H., Rees, Matthew, Watanabe, Richard M., Ader, Marilyn, Ionut, Viorica, Jackson, Anne U., Boehnke, Michael, Collins, Francis S., Bergman, Richard N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329822/ https://www.ncbi.nlm.nih.gov/pubmed/22456868 http://dx.doi.org/10.2337/dc11-1540

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