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Significance of Urinary Full-Length and Ectodomain Forms of Megalin in Patients With Type 2 Diabetes
OBJECTIVE: Megalin, an endocytic receptor in proximal tubule cells, is involved in the mechanisms of albuminuria in diabetic nephropathy (DN). To develop efficient novel biomarkers associated with the pathogenesis of DN, we investigated urinary megalin excretion in type 2 diabetes. RESEARCH DESIGN A...
Autores principales: | Ogasawara, Shinya, Hosojima, Michihiro, Kaseda, Ryohei, Kabasawa, Hideyuki, Yamamoto-Kabasawa, Keiko, Kurosawa, Hiroyuki, Sato, Hiroyoshi, Iino, Noriaki, Takeda, Tetsuro, Suzuki, Yoshiki, Narita, Ichiei, Yamagata, Kunihiro, Tomino, Yasuhiko, Gejyo, Fumitake, Hirayama, Yoshiaki, Sekine, Sakari, Saito, Akihiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329833/ https://www.ncbi.nlm.nih.gov/pubmed/22410816 http://dx.doi.org/10.2337/dc11-1684 |
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