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Significance of Urinary Full-Length and Ectodomain Forms of Megalin in Patients With Type 2 Diabetes

OBJECTIVE: Megalin, an endocytic receptor in proximal tubule cells, is involved in the mechanisms of albuminuria in diabetic nephropathy (DN). To develop efficient novel biomarkers associated with the pathogenesis of DN, we investigated urinary megalin excretion in type 2 diabetes. RESEARCH DESIGN A...

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Detalles Bibliográficos
Autores principales:	Ogasawara, Shinya, Hosojima, Michihiro, Kaseda, Ryohei, Kabasawa, Hideyuki, Yamamoto-Kabasawa, Keiko, Kurosawa, Hiroyuki, Sato, Hiroyoshi, Iino, Noriaki, Takeda, Tetsuro, Suzuki, Yoshiki, Narita, Ichiei, Yamagata, Kunihiro, Tomino, Yasuhiko, Gejyo, Fumitake, Hirayama, Yoshiaki, Sekine, Sakari, Saito, Akihiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329833/ https://www.ncbi.nlm.nih.gov/pubmed/22410816 http://dx.doi.org/10.2337/dc11-1684

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