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Relationship of Dopamine Type 2 Receptor Binding Potential With Fasting Neuroendocrine Hormones and Insulin Sensitivity in Human Obesity

OBJECTIVE: Midbrain dopamine (DA) neurons, which are involved with reward and motivation, are modulated by hormones that regulate food intake (insulin, leptin, and acyl ghrelin [AG]). We hypothesized that these hormones are associated with deficits in DA signaling in obesity. RESEARCH DESIGN AND MET...

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Detalles Bibliográficos
Autores principales: Dunn, Julia P., Kessler, Robert M., Feurer, Irene D., Volkow, Nora D., Patterson, Bruce W., Ansari, Mohammad S., Li, Rui, Marks-Shulman, Pamela, Abumrad, Naji N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329842/
https://www.ncbi.nlm.nih.gov/pubmed/22432117
http://dx.doi.org/10.2337/dc11-2250