Cargando…

AKT/mTOR as Novel Targets of Polyphenol Piceatannol Possibly Contributing to Inhibition of Proliferation of Cultured Prostate Cancer Cells

The polyphenol piceatannol has shown inhibition against tyrosine and serine/threonine kinases. Whether piceatannol also exerts activity on the mammalian target of rapamycin (mTOR), a kinase involved in growth control of eukaryotic cells, is not known. In this study, we tested the effects of piceatan...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hsieh, Tze-Chen, Lin, Chia-Yi, Lin, Hung-Yun, Wu, Joseph M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scholarly Research Network 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329858/ https://www.ncbi.nlm.nih.gov/pubmed/22567414 http://dx.doi.org/10.5402/2012/272697

Ejemplares similares

Piceatannol Suppresses the Proliferation and Induced Apoptosis of Osteosarcoma Cells Through PI3K/AKT/mTOR Pathway
por: Wang, Bin, et al.
Publicado: (2020)

Roles of Akt and ERK in mTOR-Dependent Antidepressant Effects of Vanillic Acid
por: Chuang, Han-Wen, et al.
Publicado: (2020)

PI3K-AKT-mTOR signaling in prostate cancer progression and androgen deprivation therapy resistance
por: Edlind, Merritt P, et al.
Publicado: (2014)

The Paradox of Akt-mTOR Interactions
por: Vadlakonda, Lakshmipathi, et al.
Publicado: (2013)

MYC Cooperates with AKT in Prostate Tumorigenesis and Alters Sensitivity to mTOR Inhibitors
por: Clegg, Nicola J., et al.
Publicado: (2011)

The promise of dual targeting Akt/mTOR signaling in lethal prostate cancer
por: Floc'h, Nicolas, et al.
Publicado: (2012)

Regulation of Osteoclast Growth and Fusion by mTOR/raptor and mTOR/rictor/Akt
por: Tiedemann, Kerstin, et al.
Publicado: (2017)

Targeting mTOR Signaling by Dietary Polyphenols in Obesity Prevention
por: Cao, Yunyun, et al.
Publicado: (2022)

Combined targeting of AKT and mTOR synergistically inhibits proliferation of hepatocellular carcinoma cells
por: Grabinski, Nicole, et al.
Publicado: (2012)

Arctigenin Inhibits Glioblastoma Proliferation through the AKT/mTOR Pathway and Induces Autophagy
por: Jiang, Yong'an, et al.
Publicado: (2020)

Gene polymorphisms in the PI3K/AKT/mTOR signaling pathway contribute to prostate cancer susceptibility in Chinese men
por: Liu, Ting, et al.
Publicado: (2017)

Akt activation disrupts mammary acinar architecture and enhances proliferation in an mTOR-dependent manner
por: Debnath, Jayanta, et al.
Publicado: (2003)

Prucalopride inhibits the glioma cells proliferation and induces autophagy via AKT-mTOR pathway
por: Qiao, Hong, et al.
Publicado: (2018)

TTK regulates proliferation and apoptosis of gastric cancer cells through the Akt‐mTOR pathway
por: Huang, Hongxia, et al.
Publicado: (2020)

YAP manipulates proliferation via PTEN/AKT/mTOR-mediated autophagy in lung adenocarcinomas
por: Xu, Wei, et al.
Publicado: (2021)

GPR41 Regulates the Proliferation of BRECs via the PIK3-AKT-mTOR Pathway
por: Meng, Zitong, et al.
Publicado: (2023)

EEF1D overexpression promotes osteosarcoma cell proliferation by facilitating Akt-mTOR and Akt-bad signaling
por: Cheng, Dong-dong, et al.
Publicado: (2018)

Prevention of carcinogen-induced oral cancers by polymeric black tea polyphenols via modulation of EGFR-Akt-mTOR pathway
por: Nimbalkar, Vaishnavi K., et al.
Publicado: (2022)

PI3K/Akt/mTOR Signaling Pathway in Blood Malignancies—New Therapeutic Possibilities
por: Wiese, Wojciech, et al.
Publicado: (2023)

Tumor microenvironment promotes prostate cancer cell dissemination via the Akt/mTOR pathway
por: Shi, Junlin, et al.
Publicado: (2018)

Inhibitors of the PI3K/Akt/mTOR Pathway in Prostate Cancer Chemoprevention and Intervention
por: Roudsari, Nazanin Momeni, et al.
Publicado: (2021)

Alpha-synuclein contributes to malignant progression of human meningioma via the Akt/mTOR pathway
por: Ge, Yiqin, et al.
Publicado: (2016)

Akt and mTOR in B Cell Activation and Differentiation
por: Limon, Jose J., et al.
Publicado: (2012)

Akt and mTOR mediate programmed necrosis in neurons
por: Liu, Q, et al.
Publicado: (2014)

Silencing CAPN2 Expression Inhibited Castration-Resistant Prostate Cancer Cells Proliferation and Invasion via AKT/mTOR Signal Pathway
por: Li, Pu, et al.
Publicado: (2017)

mTOR-Dependent Cell Proliferation in the Brain
por: Ryskalin, Larisa, et al.
Publicado: (2017)

Inhibition of ovarian cancer cell proliferation by Pien Tze Huang via the AKT-mTOR pathway
por: HE, FAN, et al.
Publicado: (2014)

Histone Deacetylase Inhibitors Inhibit the Proliferation of Gallbladder Carcinoma Cells by Suppressing AKT/mTOR Signaling
por: Zhang, Peng, et al.
Publicado: (2015)

Fucosyltransferase VII promotes proliferation via the EGFR/AKT/mTOR pathway in A549 cells
por: Liang, Jin-xiao, et al.
Publicado: (2017)

PODNL1 promotes cell proliferation and migration in glioma via regulating Akt/mTOR pathway
por: Geng, Yibo, et al.
Publicado: (2020)

FOXK1 Promotes Proliferation and Metastasis of Gallbladder Cancer by Activating AKT/mTOR Signaling Pathway
por: Wencong, Ma, et al.
Publicado: (2020)

UBE2C affects breast cancer proliferation through the AKT/mTOR signaling pathway
por: Lu, Zi-Nan, et al.
Publicado: (2021)

Targeting AKT/mTOR and Bcl-2 for Autophagic and Apoptosis Cell Death in Lung Cancer: Novel Activity of a Polyphenol Compound
por: Tungsukruthai, Sucharat, et al.
Publicado: (2021)

Inhibition of the AKT/mTOR pathway negatively regulates PTEN expression via miRNAs: Effect of Akt/mTOR inhibition on PTEN expression
por: Wan, Linyan, et al.
Publicado: (2022)

Ezrin promotes pancreatic cancer cell proliferation and invasion through activating the Akt/mTOR pathway and inducing YAP translocation
por: Quan, Chunji, et al.
Publicado: (2019)

Valproic acid induces autophagy by suppressing the Akt/mTOR pathway in human prostate cancer cells
por: Xia, Qinghua, et al.
Publicado: (2016)

Neuroligin 3 Regulates Dendritic Outgrowth by Modulating Akt/mTOR Signaling
por: Xu, Jing, et al.
Publicado: (2019)

PAM (PIK3/AKT/mTOR) signaling in glia: potential contributions to brain tumors in aging
por: Duggan, Michael R., et al.
Publicado: (2021)

Bufalin suppresses the proliferation and metastasis of renal cell carcinoma by inhibiting the PI3K/Akt/mTOR signaling pathway
por: Xie, Jinlin, et al.
Publicado: (2018)

PI3K/AKT/mTOR Pathway in Angiogenesis
por: Karar, Jayashree, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_651ch6mtfg117esqk40smi6jrk