Challenges in estimating percent inclusion of alternatively spliced junctions from RNA-seq data

Transcript quantification is a long-standing problem in genomics and estimating the relative abundance of alternatively-spliced isoforms from the same transcript is an important special case. Both problems have recently been illuminated by high-throughput RNA sequencing experiments which are quickly...

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Detalles Bibliográficos
Autores principales: Kakaradov, Boyko, Xiong, Hui Yuan, Lee, Leo J, Jojic, Nebojsa, Frey, Brendan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330053/
https://www.ncbi.nlm.nih.gov/pubmed/22537040
http://dx.doi.org/10.1186/1471-2105-13-S6-S11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330053/
https://www.ncbi.nlm.nih.gov/pubmed/22537040
http://dx.doi.org/10.1186/1471-2105-13-S6-S11

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