The Caenorhabditis elegans HEN1 Ortholog, HENN-1, Methylates and Stabilizes Select Subclasses of Germline Small RNAs

Small RNAs regulate diverse biological processes by directing effector proteins called Argonautes to silence complementary mRNAs. Maturation of some classes of small RNAs involves terminal 2′-O-methylation to prevent degradation. This modification is catalyzed by members of the conserved HEN1 RNA me...

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Detalles Bibliográficos
Autores principales: Billi, Allison C., Alessi, Amelia F., Khivansara, Vishal, Han, Ting, Freeberg, Mallory, Mitani, Shohei, Kim, John K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330095/
https://www.ncbi.nlm.nih.gov/pubmed/22548001
http://dx.doi.org/10.1371/journal.pgen.1002617

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