Induction of Strain-Transcending Antibodies Against Group A PfEMP1 Surface Antigens from Virulent Malaria Parasites

Sequence diversity in pathogen antigens is an obstacle to the development of interventions against many infectious diseases. In malaria caused by Plasmodium falciparum, the PfEMP1 family of variant surface antigens encoded by var genes are adhesion molecules that play a pivotal role in malaria patho...

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Detalles Bibliográficos
Autores principales: Ghumra, Ashfaq, Semblat, Jean-Philippe, Ataide, Ricardo, Kifude, Carolyne, Adams, Yvonne, Claessens, Antoine, Anong, Damian N., Bull, Peter C., Fennell, Clare, Arman, Monica, Amambua-Ngwa, Alfred, Walther, Michael, Conway, David J., Kassambara, Lalla, Doumbo, Ogobara K., Raza, Ahmed, Rowe, J. Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330128/
https://www.ncbi.nlm.nih.gov/pubmed/22532802
http://dx.doi.org/10.1371/journal.ppat.1002665

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