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Glucose-6-phosphate reduces calcium accumulation in rat brain endoplasmic reticulum

Brain cells expend large amounts of energy sequestering calcium (Ca(2+)), while loss of Ca(2+) compartmentalization leads to cell damage or death. Upon cell entry, glucose is converted to glucose-6-phosphate (G6P), a parent substrate to several metabolic major pathways, including glycolysis. In seve...

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Detalles Bibliográficos
Autores principales: Cole, Jeffrey T., Kean, William S., Pollard, Harvey B., Verma, Ajay, Watson, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330244/
https://www.ncbi.nlm.nih.gov/pubmed/22529775
http://dx.doi.org/10.3389/fnmol.2012.00051