Antipyretic activity of Radix paeoniae

The acetone extracts of Radix paeoniae (Paeonaceae) root (100 and 200 mg/kg orally) were tested in brewer's yeast-induced pyrexia in rats to assess their antipyretic activity. The pyrexia in rats was reduced significantly (P < 0.05) compared to that of control. These results indicate that th...

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Autores principales: Motwani, Sapna, Malviya, Neelesh, Goel, R.K., Dutt, K.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2007
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330835/
https://www.ncbi.nlm.nih.gov/pubmed/22557254
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author Motwani, Sapna
Malviya, Neelesh
Goel, R.K.
Dutt, K.R.
author_facet Motwani, Sapna
Malviya, Neelesh
Goel, R.K.
Dutt, K.R.
author_sort Motwani, Sapna
collection PubMed
description The acetone extracts of Radix paeoniae (Paeonaceae) root (100 and 200 mg/kg orally) were tested in brewer's yeast-induced pyrexia in rats to assess their antipyretic activity. The pyrexia in rats was reduced significantly (P < 0.05) compared to that of control. These results indicate that the extracts possess antipyretic properties. The root extract showed significant reduction in normal body temperature and yeast-provoked elevated temperature comparable to that of standard antipyretic drug paracetamol. The antipyretic effect was started at 1h and extended for at least 4h after the drug administration.
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spelling pubmed-33308352012-04-27 Antipyretic activity of Radix paeoniae Motwani, Sapna Malviya, Neelesh Goel, R.K. Dutt, K.R. Anc Sci Life Original Article The acetone extracts of Radix paeoniae (Paeonaceae) root (100 and 200 mg/kg orally) were tested in brewer's yeast-induced pyrexia in rats to assess their antipyretic activity. The pyrexia in rats was reduced significantly (P < 0.05) compared to that of control. These results indicate that the extracts possess antipyretic properties. The root extract showed significant reduction in normal body temperature and yeast-provoked elevated temperature comparable to that of standard antipyretic drug paracetamol. The antipyretic effect was started at 1h and extended for at least 4h after the drug administration. Medknow Publications & Media Pvt Ltd 2007 /pmc/articles/PMC3330835/ /pubmed/22557254 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Motwani, Sapna
Malviya, Neelesh
Goel, R.K.
Dutt, K.R.
Antipyretic activity of Radix paeoniae
title Antipyretic activity of Radix paeoniae
title_full Antipyretic activity of Radix paeoniae
title_fullStr Antipyretic activity of Radix paeoniae
title_full_unstemmed Antipyretic activity of Radix paeoniae
title_short Antipyretic activity of Radix paeoniae
title_sort antipyretic activity of radix paeoniae
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330835/
https://www.ncbi.nlm.nih.gov/pubmed/22557254
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AT malviyaneelesh antipyreticactivityofradixpaeoniae
AT goelrk antipyreticactivityofradixpaeoniae
AT duttkr antipyreticactivityofradixpaeoniae

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