Antitussive activity of ethanolic extract of Curcuma aromatica rhizomes on sulfur dioxide induced cough in mice

Ethanolic extract of rhizomes of Curcuma aromatica (Zingiberaceae) was investigated for its antitussive effect on Sulfur dioxide induced cough model in mice. The extract exhibited significant antitussive activity in a dose dependant manner. The activity was compared with the prototype antitussive ag...

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Autores principales: Marina, G.D., Kekuda, T.R Prashith, Sudarshan, S.J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2008
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330858/
https://www.ncbi.nlm.nih.gov/pubmed/22557276
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author Marina, G.D.
Kekuda, T.R Prashith
Sudarshan, S.J
author_facet Marina, G.D.
Kekuda, T.R Prashith
Sudarshan, S.J
author_sort Marina, G.D.
collection PubMed
description Ethanolic extract of rhizomes of Curcuma aromatica (Zingiberaceae) was investigated for its antitussive effect on Sulfur dioxide induced cough model in mice. The extract exhibited significant antitussive activity in a dose dependant manner. The activity was compared with the prototype antitussive agent codeine phosphate. The ethanolic extract at the dose of lOOmg. 200mg and 400mg/kg body weight, po, showed 68%, 74% and 79% of inhibition of cough with respect to control group.
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spelling pubmed-33308582012-04-27 Antitussive activity of ethanolic extract of Curcuma aromatica rhizomes on sulfur dioxide induced cough in mice Marina, G.D. Kekuda, T.R Prashith Sudarshan, S.J Anc Sci Life Original Article Ethanolic extract of rhizomes of Curcuma aromatica (Zingiberaceae) was investigated for its antitussive effect on Sulfur dioxide induced cough model in mice. The extract exhibited significant antitussive activity in a dose dependant manner. The activity was compared with the prototype antitussive agent codeine phosphate. The ethanolic extract at the dose of lOOmg. 200mg and 400mg/kg body weight, po, showed 68%, 74% and 79% of inhibition of cough with respect to control group. Medknow Publications & Media Pvt Ltd 2008 /pmc/articles/PMC3330858/ /pubmed/22557276 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Marina, G.D.
Kekuda, T.R Prashith
Sudarshan, S.J
Antitussive activity of ethanolic extract of Curcuma aromatica rhizomes on sulfur dioxide induced cough in mice
title Antitussive activity of ethanolic extract of Curcuma aromatica rhizomes on sulfur dioxide induced cough in mice
title_full Antitussive activity of ethanolic extract of Curcuma aromatica rhizomes on sulfur dioxide induced cough in mice
title_fullStr Antitussive activity of ethanolic extract of Curcuma aromatica rhizomes on sulfur dioxide induced cough in mice
title_full_unstemmed Antitussive activity of ethanolic extract of Curcuma aromatica rhizomes on sulfur dioxide induced cough in mice
title_short Antitussive activity of ethanolic extract of Curcuma aromatica rhizomes on sulfur dioxide induced cough in mice
title_sort antitussive activity of ethanolic extract of curcuma aromatica rhizomes on sulfur dioxide induced cough in mice
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330858/
https://www.ncbi.nlm.nih.gov/pubmed/22557276
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