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PHYTO-PHARMACOGNOSTICAL INVESTIGATION AND EVALUATION OF ANTI-INFLAMMATORY AND SEDATIVE HYPNOTIC ACTIVITY OF THE LEAVES OF ERYTHRINA INDICA Lam

Pharmacognostical investigations were carried out on the Erythrina indica leaves, followed by phytochemical investigation. On the methanolic extract of leaves, TLC was performed and indole alkaloids were identified with selected solvent system. The UV analysis was also performed on the components co...

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Detalles Bibliográficos
Autores principales: Verma, S. M., Amrisha, Prakash, J., Sah, V.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330900/
https://www.ncbi.nlm.nih.gov/pubmed/22557197
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author Verma, S. M.
Amrisha,
Prakash, J.
Sah, V.K.
author_facet Verma, S. M.
Amrisha,
Prakash, J.
Sah, V.K.
author_sort Verma, S. M.
collection PubMed
description Pharmacognostical investigations were carried out on the Erythrina indica leaves, followed by phytochemical investigation. On the methanolic extract of leaves, TLC was performed and indole alkaloids were identified with selected solvent system. The UV analysis was also performed on the components confirming the presence of the indole nucleus. Anti-inflammatory activity was carried out on albino rats. Further, anti-inflammatory activity was compared to that of the standard drug indomethacin and percent inhibition of oedema was determined. Sedative hypnotic activity was also evaluated using pentobarbital which showed mild sedation.
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spelling pubmed-33309002012-04-27 PHYTO-PHARMACOGNOSTICAL INVESTIGATION AND EVALUATION OF ANTI-INFLAMMATORY AND SEDATIVE HYPNOTIC ACTIVITY OF THE LEAVES OF ERYTHRINA INDICA Lam Verma, S. M. Amrisha, Prakash, J. Sah, V.K. Anc Sci Life Original Article Pharmacognostical investigations were carried out on the Erythrina indica leaves, followed by phytochemical investigation. On the methanolic extract of leaves, TLC was performed and indole alkaloids were identified with selected solvent system. The UV analysis was also performed on the components confirming the presence of the indole nucleus. Anti-inflammatory activity was carried out on albino rats. Further, anti-inflammatory activity was compared to that of the standard drug indomethacin and percent inhibition of oedema was determined. Sedative hypnotic activity was also evaluated using pentobarbital which showed mild sedation. Medknow Publications & Media Pvt Ltd 2005 /pmc/articles/PMC3330900/ /pubmed/22557197 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Verma, S. M.
Amrisha,
Prakash, J.
Sah, V.K.
PHYTO-PHARMACOGNOSTICAL INVESTIGATION AND EVALUATION OF ANTI-INFLAMMATORY AND SEDATIVE HYPNOTIC ACTIVITY OF THE LEAVES OF ERYTHRINA INDICA Lam
title PHYTO-PHARMACOGNOSTICAL INVESTIGATION AND EVALUATION OF ANTI-INFLAMMATORY AND SEDATIVE HYPNOTIC ACTIVITY OF THE LEAVES OF ERYTHRINA INDICA Lam
title_full PHYTO-PHARMACOGNOSTICAL INVESTIGATION AND EVALUATION OF ANTI-INFLAMMATORY AND SEDATIVE HYPNOTIC ACTIVITY OF THE LEAVES OF ERYTHRINA INDICA Lam
title_fullStr PHYTO-PHARMACOGNOSTICAL INVESTIGATION AND EVALUATION OF ANTI-INFLAMMATORY AND SEDATIVE HYPNOTIC ACTIVITY OF THE LEAVES OF ERYTHRINA INDICA Lam
title_full_unstemmed PHYTO-PHARMACOGNOSTICAL INVESTIGATION AND EVALUATION OF ANTI-INFLAMMATORY AND SEDATIVE HYPNOTIC ACTIVITY OF THE LEAVES OF ERYTHRINA INDICA Lam
title_short PHYTO-PHARMACOGNOSTICAL INVESTIGATION AND EVALUATION OF ANTI-INFLAMMATORY AND SEDATIVE HYPNOTIC ACTIVITY OF THE LEAVES OF ERYTHRINA INDICA Lam
title_sort phyto-pharmacognostical investigation and evaluation of anti-inflammatory and sedative hypnotic activity of the leaves of erythrina indica lam
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330900/
https://www.ncbi.nlm.nih.gov/pubmed/22557197
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