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PHYTO-PHARMACOGNOSTICAL INVESTIGATION AND EVALUATION OF ANTI-INFLAMMATORY AND SEDATIVE HYPNOTIC ACTIVITY OF THE LEAVES OF ERYTHRINA INDICA Lam
Pharmacognostical investigations were carried out on the Erythrina indica leaves, followed by phytochemical investigation. On the methanolic extract of leaves, TLC was performed and indole alkaloids were identified with selected solvent system. The UV analysis was also performed on the components co...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330900/ https://www.ncbi.nlm.nih.gov/pubmed/22557197 |
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author | Verma, S. M. Amrisha, Prakash, J. Sah, V.K. |
author_facet | Verma, S. M. Amrisha, Prakash, J. Sah, V.K. |
author_sort | Verma, S. M. |
collection | PubMed |
description | Pharmacognostical investigations were carried out on the Erythrina indica leaves, followed by phytochemical investigation. On the methanolic extract of leaves, TLC was performed and indole alkaloids were identified with selected solvent system. The UV analysis was also performed on the components confirming the presence of the indole nucleus. Anti-inflammatory activity was carried out on albino rats. Further, anti-inflammatory activity was compared to that of the standard drug indomethacin and percent inhibition of oedema was determined. Sedative hypnotic activity was also evaluated using pentobarbital which showed mild sedation. |
format | Online Article Text |
id | pubmed-3330900 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2005 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-33309002012-04-27 PHYTO-PHARMACOGNOSTICAL INVESTIGATION AND EVALUATION OF ANTI-INFLAMMATORY AND SEDATIVE HYPNOTIC ACTIVITY OF THE LEAVES OF ERYTHRINA INDICA Lam Verma, S. M. Amrisha, Prakash, J. Sah, V.K. Anc Sci Life Original Article Pharmacognostical investigations were carried out on the Erythrina indica leaves, followed by phytochemical investigation. On the methanolic extract of leaves, TLC was performed and indole alkaloids were identified with selected solvent system. The UV analysis was also performed on the components confirming the presence of the indole nucleus. Anti-inflammatory activity was carried out on albino rats. Further, anti-inflammatory activity was compared to that of the standard drug indomethacin and percent inhibition of oedema was determined. Sedative hypnotic activity was also evaluated using pentobarbital which showed mild sedation. Medknow Publications & Media Pvt Ltd 2005 /pmc/articles/PMC3330900/ /pubmed/22557197 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Verma, S. M. Amrisha, Prakash, J. Sah, V.K. PHYTO-PHARMACOGNOSTICAL INVESTIGATION AND EVALUATION OF ANTI-INFLAMMATORY AND SEDATIVE HYPNOTIC ACTIVITY OF THE LEAVES OF ERYTHRINA INDICA Lam |
title | PHYTO-PHARMACOGNOSTICAL INVESTIGATION AND EVALUATION OF ANTI-INFLAMMATORY AND SEDATIVE HYPNOTIC ACTIVITY OF THE LEAVES OF ERYTHRINA INDICA Lam |
title_full | PHYTO-PHARMACOGNOSTICAL INVESTIGATION AND EVALUATION OF ANTI-INFLAMMATORY AND SEDATIVE HYPNOTIC ACTIVITY OF THE LEAVES OF ERYTHRINA INDICA Lam |
title_fullStr | PHYTO-PHARMACOGNOSTICAL INVESTIGATION AND EVALUATION OF ANTI-INFLAMMATORY AND SEDATIVE HYPNOTIC ACTIVITY OF THE LEAVES OF ERYTHRINA INDICA Lam |
title_full_unstemmed | PHYTO-PHARMACOGNOSTICAL INVESTIGATION AND EVALUATION OF ANTI-INFLAMMATORY AND SEDATIVE HYPNOTIC ACTIVITY OF THE LEAVES OF ERYTHRINA INDICA Lam |
title_short | PHYTO-PHARMACOGNOSTICAL INVESTIGATION AND EVALUATION OF ANTI-INFLAMMATORY AND SEDATIVE HYPNOTIC ACTIVITY OF THE LEAVES OF ERYTHRINA INDICA Lam |
title_sort | phyto-pharmacognostical investigation and evaluation of anti-inflammatory and sedative hypnotic activity of the leaves of erythrina indica lam |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330900/ https://www.ncbi.nlm.nih.gov/pubmed/22557197 |
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