Modulatory effects of lxora coccinea flower on Cyclophosphamidetoxicity in tumour bearing mice

The active fraction (AF) from lxora coccinea flowers prevented the decrease in haemoglobin levels and leucocyte counts of Dalton's lymphoma tumour bearing mice, treated with cyclophosphamide (CYP). It also significantly increased the life span of tumour bearing mice, treated with cyclophosphami...

Descripción completa

Detalles Bibliográficos
Autores principales: Latha, P G, Suja, S.R., Panikkar, K R, Rajasekharan, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2004
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330984/
https://www.ncbi.nlm.nih.gov/pubmed/22557138
Descripción
Sumario:The active fraction (AF) from lxora coccinea flowers prevented the decrease in haemoglobin levels and leucocyte counts of Dalton's lymphoma tumour bearing mice, treated with cyclophosphamide (CYP). It also significantly increased the life span of tumour bearing mice, treated with cyclophosphamide. Serum glutamate pyruvate transaminase (SGPT) and serum alkaline phosphatase (SAKP) levels of tumour bearing mice treated with CYP were decreased significantly by combination therapy with I.coccinea AF. indicating protection against hepatic toxicity.

Ejemplares similares