Modulatory effects of lxora coccinea flower on Cyclophosphamidetoxicity in tumour bearing mice

The active fraction (AF) from lxora coccinea flowers prevented the decrease in haemoglobin levels and leucocyte counts of Dalton's lymphoma tumour bearing mice, treated with cyclophosphamide (CYP). It also significantly increased the life span of tumour bearing mice, treated with cyclophosphami...

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Autores principales: Latha, P G, Suja, S.R., Panikkar, K R, Rajasekharan, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2004
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330984/
https://www.ncbi.nlm.nih.gov/pubmed/22557138
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author Latha, P G
Suja, S.R.
Panikkar, K R
Rajasekharan, S
author_facet Latha, P G
Suja, S.R.
Panikkar, K R
Rajasekharan, S
author_sort Latha, P G
collection PubMed
description The active fraction (AF) from lxora coccinea flowers prevented the decrease in haemoglobin levels and leucocyte counts of Dalton's lymphoma tumour bearing mice, treated with cyclophosphamide (CYP). It also significantly increased the life span of tumour bearing mice, treated with cyclophosphamide. Serum glutamate pyruvate transaminase (SGPT) and serum alkaline phosphatase (SAKP) levels of tumour bearing mice treated with CYP were decreased significantly by combination therapy with I.coccinea AF. indicating protection against hepatic toxicity.
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spelling pubmed-33309842012-04-27 Modulatory effects of lxora coccinea flower on Cyclophosphamidetoxicity in tumour bearing mice Latha, P G Suja, S.R. Panikkar, K R Rajasekharan, S Anc Sci Life Original Article The active fraction (AF) from lxora coccinea flowers prevented the decrease in haemoglobin levels and leucocyte counts of Dalton's lymphoma tumour bearing mice, treated with cyclophosphamide (CYP). It also significantly increased the life span of tumour bearing mice, treated with cyclophosphamide. Serum glutamate pyruvate transaminase (SGPT) and serum alkaline phosphatase (SAKP) levels of tumour bearing mice treated with CYP were decreased significantly by combination therapy with I.coccinea AF. indicating protection against hepatic toxicity. Medknow Publications & Media Pvt Ltd 2004 /pmc/articles/PMC3330984/ /pubmed/22557138 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Latha, P G
Suja, S.R.
Panikkar, K R
Rajasekharan, S
Modulatory effects of lxora coccinea flower on Cyclophosphamidetoxicity in tumour bearing mice
title Modulatory effects of lxora coccinea flower on Cyclophosphamidetoxicity in tumour bearing mice
title_full Modulatory effects of lxora coccinea flower on Cyclophosphamidetoxicity in tumour bearing mice
title_fullStr Modulatory effects of lxora coccinea flower on Cyclophosphamidetoxicity in tumour bearing mice
title_full_unstemmed Modulatory effects of lxora coccinea flower on Cyclophosphamidetoxicity in tumour bearing mice
title_short Modulatory effects of lxora coccinea flower on Cyclophosphamidetoxicity in tumour bearing mice
title_sort modulatory effects of lxora coccinea flower on cyclophosphamidetoxicity in tumour bearing mice
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330984/
https://www.ncbi.nlm.nih.gov/pubmed/22557138
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AT panikkarkr modulatoryeffectsoflxoracoccineafloweroncyclophosphamidetoxicityintumourbearingmice
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