PURGATIVE AND ANTI-INFLAMMATORY ACTIVITIES OF CASSIA DIDYMOBOTRYA, FRESEN

Aqueous and ethanol extracts of cassia didymobotraya were investigated for purgative and anit-inflammatory activities in albino mice and rats, respectively at a dose of 100 mg/kg body weight. Anti-inflammatory activity was screened by 1% carageenan induced paw edema method and purgative activity was...

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Detalles Bibliográficos
Autores principales: Mahadevan, N., Upendra, B.G., Subburaju, T., Elango, K., Suresh, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2002
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330987/
https://www.ncbi.nlm.nih.gov/pubmed/22557069
Descripción
Sumario:Aqueous and ethanol extracts of cassia didymobotraya were investigated for purgative and anit-inflammatory activities in albino mice and rats, respectively at a dose of 100 mg/kg body weight. Anti-inflammatory activity was screened by 1% carageenan induced paw edema method and purgative activity was screened by the method described by Akah etal, Both the extracts exhibited significant purgative and anti-inflammatory activities, which are comparable to standard drugs, Senna (20mg/kg) and indomethacin (20mg/kg). Ethanol extract showed higher purgative and anti-inflammatory than aqueous extract. The percentage of protection of aqueous, ethanol extracts and indomethacin were found to be 35.29,37.25 and 43.13.

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