PURGATIVE AND ANTI-INFLAMMATORY ACTIVITIES OF CASSIA DIDYMOBOTRYA, FRESEN

Aqueous and ethanol extracts of cassia didymobotraya were investigated for purgative and anit-inflammatory activities in albino mice and rats, respectively at a dose of 100 mg/kg body weight. Anti-inflammatory activity was screened by 1% carageenan induced paw edema method and purgative activity was...

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Autores principales: Mahadevan, N., Upendra, B.G., Subburaju, T., Elango, K., Suresh, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2002
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330987/
https://www.ncbi.nlm.nih.gov/pubmed/22557069
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author Mahadevan, N.
Upendra, B.G.
Subburaju, T.
Elango, K.
Suresh, B.
author_facet Mahadevan, N.
Upendra, B.G.
Subburaju, T.
Elango, K.
Suresh, B.
author_sort Mahadevan, N.
collection PubMed
description Aqueous and ethanol extracts of cassia didymobotraya were investigated for purgative and anit-inflammatory activities in albino mice and rats, respectively at a dose of 100 mg/kg body weight. Anti-inflammatory activity was screened by 1% carageenan induced paw edema method and purgative activity was screened by the method described by Akah etal, Both the extracts exhibited significant purgative and anti-inflammatory activities, which are comparable to standard drugs, Senna (20mg/kg) and indomethacin (20mg/kg). Ethanol extract showed higher purgative and anti-inflammatory than aqueous extract. The percentage of protection of aqueous, ethanol extracts and indomethacin were found to be 35.29,37.25 and 43.13.
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spelling pubmed-33309872012-04-27 PURGATIVE AND ANTI-INFLAMMATORY ACTIVITIES OF CASSIA DIDYMOBOTRYA, FRESEN Mahadevan, N. Upendra, B.G. Subburaju, T. Elango, K. Suresh, B. Anc Sci Life Original Article Aqueous and ethanol extracts of cassia didymobotraya were investigated for purgative and anit-inflammatory activities in albino mice and rats, respectively at a dose of 100 mg/kg body weight. Anti-inflammatory activity was screened by 1% carageenan induced paw edema method and purgative activity was screened by the method described by Akah etal, Both the extracts exhibited significant purgative and anti-inflammatory activities, which are comparable to standard drugs, Senna (20mg/kg) and indomethacin (20mg/kg). Ethanol extract showed higher purgative and anti-inflammatory than aqueous extract. The percentage of protection of aqueous, ethanol extracts and indomethacin were found to be 35.29,37.25 and 43.13. Medknow Publications & Media Pvt Ltd 2002 /pmc/articles/PMC3330987/ /pubmed/22557069 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Mahadevan, N.
Upendra, B.G.
Subburaju, T.
Elango, K.
Suresh, B.
PURGATIVE AND ANTI-INFLAMMATORY ACTIVITIES OF CASSIA DIDYMOBOTRYA, FRESEN
title PURGATIVE AND ANTI-INFLAMMATORY ACTIVITIES OF CASSIA DIDYMOBOTRYA, FRESEN
title_full PURGATIVE AND ANTI-INFLAMMATORY ACTIVITIES OF CASSIA DIDYMOBOTRYA, FRESEN
title_fullStr PURGATIVE AND ANTI-INFLAMMATORY ACTIVITIES OF CASSIA DIDYMOBOTRYA, FRESEN
title_full_unstemmed PURGATIVE AND ANTI-INFLAMMATORY ACTIVITIES OF CASSIA DIDYMOBOTRYA, FRESEN
title_short PURGATIVE AND ANTI-INFLAMMATORY ACTIVITIES OF CASSIA DIDYMOBOTRYA, FRESEN
title_sort purgative and anti-inflammatory activities of cassia didymobotrya, fresen
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330987/
https://www.ncbi.nlm.nih.gov/pubmed/22557069
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