DIURETIC ACTIVITY OF COLEUS AROMATICUS BENTH ON RATS

Water extract of the leaves of Coleus Aromaticus Benth was tested for its diuretic activity in male albino rats. The study was carried out on normal rats using furosemide as a standard reference drug. Rats were treated with furosemide (4 mg/kg. p.o) and Coleus aromaticus (0.5 g/kg and 1.0 g/kg, p/o)...

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Detalles Bibliográficos
Autores principales: Sur, T.K., Pandit, S., Biswas, T.K., Ghosh, R.B., Bhattacharyya, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2003
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331014/
https://www.ncbi.nlm.nih.gov/pubmed/22557102
Descripción
Sumario:Water extract of the leaves of Coleus Aromaticus Benth was tested for its diuretic activity in male albino rats. The study was carried out on normal rats using furosemide as a standard reference drug. Rats were treated with furosemide (4 mg/kg. p.o) and Coleus aromaticus (0.5 g/kg and 1.0 g/kg, p/o). Urine was collected and its volume was recorded. Urinary levels of sodium, potassium and chloride were estimated. Treatment with Coleus aromaticus produced diuresis. The urine output and electrolytes concentration was significantly increased. Hence, it is suggested, Coleus aromaticus leaves has diuretic activity on rats.

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