PHARMACOLOGICAL INVESTIGATIONS ON AGLAIA ROXBURGHIANA (W. &.A) MIQ. VAR. BEDDOMEI LEAVES

Aglaia roxburghiana is a traditional remedy for a variety of diseases. The ethanolic extract of the leaves was screened for related activities were upon it exhibited significant anti-inflammatory activity in rats in acute and chronic models. There was no acute toxicity in mice upto 2g/kg. The extrac...

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Detalles Bibliográficos
Autores principales: Janaki, S., Vijayasekaran, S., Rao, R. Bima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 1998
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331066/
https://www.ncbi.nlm.nih.gov/pubmed/22556870
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author Janaki, S.
Vijayasekaran, S.
Rao, R. Bima
author_facet Janaki, S.
Vijayasekaran, S.
Rao, R. Bima
author_sort Janaki, S.
collection PubMed
description Aglaia roxburghiana is a traditional remedy for a variety of diseases. The ethanolic extract of the leaves was screened for related activities were upon it exhibited significant anti-inflammatory activity in rats in acute and chronic models. There was no acute toxicity in mice upto 2g/kg. The extract protected the mast cell deregulation by compound 48/80 and inhibited histamine induced contractions in guinea pig ileum. The data obtained in this study suggest that the extract ma act by stabilizing mast cells ad blocking histamine receptors.
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spelling pubmed-33310662012-04-27 PHARMACOLOGICAL INVESTIGATIONS ON AGLAIA ROXBURGHIANA (W. &.A) MIQ. VAR. BEDDOMEI LEAVES Janaki, S. Vijayasekaran, S. Rao, R. Bima Anc Sci Life Original Article Aglaia roxburghiana is a traditional remedy for a variety of diseases. The ethanolic extract of the leaves was screened for related activities were upon it exhibited significant anti-inflammatory activity in rats in acute and chronic models. There was no acute toxicity in mice upto 2g/kg. The extract protected the mast cell deregulation by compound 48/80 and inhibited histamine induced contractions in guinea pig ileum. The data obtained in this study suggest that the extract ma act by stabilizing mast cells ad blocking histamine receptors. Medknow Publications & Media Pvt Ltd 1998 /pmc/articles/PMC3331066/ /pubmed/22556870 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Janaki, S.
Vijayasekaran, S.
Rao, R. Bima
PHARMACOLOGICAL INVESTIGATIONS ON AGLAIA ROXBURGHIANA (W. &.A) MIQ. VAR. BEDDOMEI LEAVES
title PHARMACOLOGICAL INVESTIGATIONS ON AGLAIA ROXBURGHIANA (W. &.A) MIQ. VAR. BEDDOMEI LEAVES
title_full PHARMACOLOGICAL INVESTIGATIONS ON AGLAIA ROXBURGHIANA (W. &.A) MIQ. VAR. BEDDOMEI LEAVES
title_fullStr PHARMACOLOGICAL INVESTIGATIONS ON AGLAIA ROXBURGHIANA (W. &.A) MIQ. VAR. BEDDOMEI LEAVES
title_full_unstemmed PHARMACOLOGICAL INVESTIGATIONS ON AGLAIA ROXBURGHIANA (W. &.A) MIQ. VAR. BEDDOMEI LEAVES
title_short PHARMACOLOGICAL INVESTIGATIONS ON AGLAIA ROXBURGHIANA (W. &.A) MIQ. VAR. BEDDOMEI LEAVES
title_sort pharmacological investigations on aglaia roxburghiana (w. &.a) miq. var. beddomei leaves
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331066/
https://www.ncbi.nlm.nih.gov/pubmed/22556870
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