LIVER FUNCTION ENZYMES AT THE LD(50) LEVEL OF THE WATER AND METHANOL EXTRACTS OF STREBULUS ASPERON MICE

The LD(50) of the water and methanolic extractable portion of S. asper was 230mgm/kgm body weight and 200 mgm/kgm body weight respectively. Mice treated with Saw1 and SaM1 portion of S. asper showed an increase in GOT,GPT acid phosphatase, alkaline phosphatase and β-glucuronidase in the liver after...

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Detalles Bibliográficos
Autores principales: Mathai, Annie, Devi, K.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 1997
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331082/
https://www.ncbi.nlm.nih.gov/pubmed/22556820
Descripción
Sumario:The LD(50) of the water and methanolic extractable portion of S. asper was 230mgm/kgm body weight and 200 mgm/kgm body weight respectively. Mice treated with Saw1 and SaM1 portion of S. asper showed an increase in GOT,GPT acid phosphatase, alkaline phosphatase and β-glucuronidase in the liver after 24hrs of drug treatment, the increase being ore in SaM1 treated group. The enzyme activity slowly recovered at 48 and 72 hrs. But were not reaching the corresponding control values after 72 hrs.

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