CYTOTOXIC AND ANTI –TUMOUR PROPERTIES OF ETHANOLIC EXTRACT OF BACOPA MONNIERI (L) PENN

Bacopa Monnieri (L) penn. Belongs to the family scrophulariaceae is commonly used in Ayurvedic system of medicine to treat various disease. The present stud examines the anti-tumous effect of ethanolic extract of whole plant bacopa monnieri (L) (EEMB) by in vitro short term chemosensitivity and in v...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, E.P., Elshurafa, Allam Ahmed, Elango, K., Subburaju, T., Suresh, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 1998
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331112/
https://www.ncbi.nlm.nih.gov/pubmed/22556847
_version_ 1782230025166127104
author Kumar, E.P.
Elshurafa, Allam Ahmed
Elango, K.
Subburaju, T.
Suresh, B.
author_facet Kumar, E.P.
Elshurafa, Allam Ahmed
Elango, K.
Subburaju, T.
Suresh, B.
author_sort Kumar, E.P.
collection PubMed
description Bacopa Monnieri (L) penn. Belongs to the family scrophulariaceae is commonly used in Ayurvedic system of medicine to treat various disease. The present stud examines the anti-tumous effect of ethanolic extract of whole plant bacopa monnieri (L) (EEMB) by in vitro short term chemosensitivity and in vivo tumous model test systems. EEBM dose dependently inhibited the proliferation of transformed cell lines significantly. Fifty percent dose on 3 hour exposure to EEBM was 150 μg/ml for Dalton's lymphoma ascites tumour cells (Dla). Oral administration of the EEBM retarded the development of solid tumour and restored the altered hematological parameters near to normal.
format Online
Article
Text
id pubmed-3331112
institution National Center for Biotechnology Information
language English
publishDate 1998
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-33311122012-04-27 CYTOTOXIC AND ANTI –TUMOUR PROPERTIES OF ETHANOLIC EXTRACT OF BACOPA MONNIERI (L) PENN Kumar, E.P. Elshurafa, Allam Ahmed Elango, K. Subburaju, T. Suresh, B. Anc Sci Life Original Article Bacopa Monnieri (L) penn. Belongs to the family scrophulariaceae is commonly used in Ayurvedic system of medicine to treat various disease. The present stud examines the anti-tumous effect of ethanolic extract of whole plant bacopa monnieri (L) (EEMB) by in vitro short term chemosensitivity and in vivo tumous model test systems. EEBM dose dependently inhibited the proliferation of transformed cell lines significantly. Fifty percent dose on 3 hour exposure to EEBM was 150 μg/ml for Dalton's lymphoma ascites tumour cells (Dla). Oral administration of the EEBM retarded the development of solid tumour and restored the altered hematological parameters near to normal. Medknow Publications & Media Pvt Ltd 1998 /pmc/articles/PMC3331112/ /pubmed/22556847 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kumar, E.P.
Elshurafa, Allam Ahmed
Elango, K.
Subburaju, T.
Suresh, B.
CYTOTOXIC AND ANTI –TUMOUR PROPERTIES OF ETHANOLIC EXTRACT OF BACOPA MONNIERI (L) PENN
title CYTOTOXIC AND ANTI –TUMOUR PROPERTIES OF ETHANOLIC EXTRACT OF BACOPA MONNIERI (L) PENN
title_full CYTOTOXIC AND ANTI –TUMOUR PROPERTIES OF ETHANOLIC EXTRACT OF BACOPA MONNIERI (L) PENN
title_fullStr CYTOTOXIC AND ANTI –TUMOUR PROPERTIES OF ETHANOLIC EXTRACT OF BACOPA MONNIERI (L) PENN
title_full_unstemmed CYTOTOXIC AND ANTI –TUMOUR PROPERTIES OF ETHANOLIC EXTRACT OF BACOPA MONNIERI (L) PENN
title_short CYTOTOXIC AND ANTI –TUMOUR PROPERTIES OF ETHANOLIC EXTRACT OF BACOPA MONNIERI (L) PENN
title_sort cytotoxic and anti –tumour properties of ethanolic extract of bacopa monnieri (l) penn
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331112/
https://www.ncbi.nlm.nih.gov/pubmed/22556847
work_keys_str_mv AT kumarep cytotoxicandantitumourpropertiesofethanolicextractofbacopamonnierilpenn
AT elshurafaallamahmed cytotoxicandantitumourpropertiesofethanolicextractofbacopamonnierilpenn
AT elangok cytotoxicandantitumourpropertiesofethanolicextractofbacopamonnierilpenn
AT subburajut cytotoxicandantitumourpropertiesofethanolicextractofbacopamonnierilpenn
AT sureshb cytotoxicandantitumourpropertiesofethanolicextractofbacopamonnierilpenn

Ejemplares similares