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ANTI – TUMOUR EFFECT OF BERBERIS ASIATICA ROXB. EX. DC. ON DALTON'S LYMPHOMA ASCITE
Berberis asiatica Roxb. Ex. Dc., non Griff. Belongs to the family berberidaceae commonly occurring in the dry outer Himalaya, Assam etc. Roots along with stem bark s a reputed drug in Ayurvedic medicine contain several alkaloids. 50% Ethaolnic extract of roots reported to posses anti-cancer activity...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331127/ https://www.ncbi.nlm.nih.gov/pubmed/22556858 |
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author | Kumar, E.P. Elshurafa, Allam Ahmed Elango, K. Subburaju, T. Suresh, B. |
author_facet | Kumar, E.P. Elshurafa, Allam Ahmed Elango, K. Subburaju, T. Suresh, B. |
author_sort | Kumar, E.P. |
collection | PubMed |
description | Berberis asiatica Roxb. Ex. Dc., non Griff. Belongs to the family berberidaceae commonly occurring in the dry outer Himalaya, Assam etc. Roots along with stem bark s a reputed drug in Ayurvedic medicine contain several alkaloids. 50% Ethaolnic extract of roots reported to posses anti-cancer activity. The present study examines the antitumour effect of ethanolic root extract (BRE) against Dalton's lymphoma ascites tumour cells and solid tumour in swiss albino mice, A significant enhancement of mean survival time of BRE treated tumour bearing mice was found. Oral administration of BRE reduced the solid tumour induced by DLE and restored the altered haematological parameters to normal. |
format | Online Article Text |
id | pubmed-3331127 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1998 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-33311272012-04-27 ANTI – TUMOUR EFFECT OF BERBERIS ASIATICA ROXB. EX. DC. ON DALTON'S LYMPHOMA ASCITE Kumar, E.P. Elshurafa, Allam Ahmed Elango, K. Subburaju, T. Suresh, B. Anc Sci Life Original Article Berberis asiatica Roxb. Ex. Dc., non Griff. Belongs to the family berberidaceae commonly occurring in the dry outer Himalaya, Assam etc. Roots along with stem bark s a reputed drug in Ayurvedic medicine contain several alkaloids. 50% Ethaolnic extract of roots reported to posses anti-cancer activity. The present study examines the antitumour effect of ethanolic root extract (BRE) against Dalton's lymphoma ascites tumour cells and solid tumour in swiss albino mice, A significant enhancement of mean survival time of BRE treated tumour bearing mice was found. Oral administration of BRE reduced the solid tumour induced by DLE and restored the altered haematological parameters to normal. Medknow Publications & Media Pvt Ltd 1998 /pmc/articles/PMC3331127/ /pubmed/22556858 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Kumar, E.P. Elshurafa, Allam Ahmed Elango, K. Subburaju, T. Suresh, B. ANTI – TUMOUR EFFECT OF BERBERIS ASIATICA ROXB. EX. DC. ON DALTON'S LYMPHOMA ASCITE |
title | ANTI – TUMOUR EFFECT OF BERBERIS ASIATICA ROXB. EX. DC. ON DALTON'S LYMPHOMA ASCITE |
title_full | ANTI – TUMOUR EFFECT OF BERBERIS ASIATICA ROXB. EX. DC. ON DALTON'S LYMPHOMA ASCITE |
title_fullStr | ANTI – TUMOUR EFFECT OF BERBERIS ASIATICA ROXB. EX. DC. ON DALTON'S LYMPHOMA ASCITE |
title_full_unstemmed | ANTI – TUMOUR EFFECT OF BERBERIS ASIATICA ROXB. EX. DC. ON DALTON'S LYMPHOMA ASCITE |
title_short | ANTI – TUMOUR EFFECT OF BERBERIS ASIATICA ROXB. EX. DC. ON DALTON'S LYMPHOMA ASCITE |
title_sort | anti – tumour effect of berberis asiatica roxb. ex. dc. on dalton's lymphoma ascite |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331127/ https://www.ncbi.nlm.nih.gov/pubmed/22556858 |
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