IMMUNOPOTENTIATION BY IMMU 21 IN IMMUNOCOMPROMISED RATS

IMMU -21 a polyherbal immunomodulator effectively enhanced the immune status of animals treated with cytotoxic and immunosuppressive agents like cyclophosphamide and azathioprine. Leucopenia, lymphopenia and neutropenia in rats induced by cyclophosphamide were significantly minimized in IMMU-21 pre treated animals. IMMU-21 strengthened the host immune status against bacterial endotoxin. Cell mediated immune response was also found to be maintained at the normal level in immunocompromised mice treated with IMMU 21. The results of the experiments are of immense clinical significance IMMU -21 shows promise as a useful immunoadjuvant which may have various therapeutic applications.