EFFECT OF SHORT DURATION CAFFEINE TREATMENT ON THE JEJUNUM OF ADULT ALBINO RATS

The effect of the short duration (21 days) of caffeine at two different doses (12 mg & 30 mg/kg body weight/day) on the activities of adenosine triphosphatases in jejunum was studied. The activity of Na+, K+ -dependent ATP-ase was reduced significantly in the upper jejunal mucosal and serosal la...

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Detalles Bibliográficos
Autores principales: Pushpalatha, R., Tulasi, K. Sri, Vanithakumari, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 1995
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331195/
https://www.ncbi.nlm.nih.gov/pubmed/22556727
Descripción
Sumario:The effect of the short duration (21 days) of caffeine at two different doses (12 mg & 30 mg/kg body weight/day) on the activities of adenosine triphosphatases in jejunum was studied. The activity of Na+, K+ -dependent ATP-ase was reduced significantly in the upper jejunal mucosal and serosal layers of low an high dose groups. Such effect was observed only in the lower jejunal serosal layer while a marked reduction in the activity of Mg2+ATP –ase was seen in mucosal and serosal layers of the jejunum at both doses. There was a significant increase in the activities of Ca2+-dependent and HCO3-dependent ATP –ases in these regions of the lower jejunum.

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