CHANGES OBSERVED IN SERUM MARKER ENZYMES AND PLASMA GLYCOPROTEINS IN FIBROSARCOMA AND IN TREATMENT WITH AN INDIGENOUS DRUG “PANCHAKAVVYAM” IN RATS

“Panchakavvyam”, an indigenous preparation, has been referred to in ancient vedic literature of India, as having anticarcinogenic influence to the system, suffering from cancer. The levels of the marker enzymes such as lactate dehydrogenase and alkaline phospeatase in serum and glycoprotein levels in plasma are analysed. They are significantly reduced in the drug treated group, suggesting that this drug may have anticarcinogenic properties. Histopathological observations made on the tumor tissue of the drug-treated animals and the untreated ones, attribute concrete evidence to our inference, explaining more clearly, the observations made on the enzyme levels.