‘ANTIANDROGENIC PROPERTIES OF NEEM SEED OIL (AZADIRACHTA INDICA) IN MALE RAT AND RABBI’

Azadirachta indica (Neem) seed oil brings about a significant diminution in spermatozoan motility and density. It leads to reduction of fertility rate in rats and rabbits. The body weight of the animals remain unaffected but the weights of reproductive oranges declined. Reduction of cauda epididymal...

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Detalles Bibliográficos
Autores principales: Sharma, J. D., Jha, R. K., Gupta, Ira, Jain, Prabha, Dixit, V.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 1987
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331377/
https://www.ncbi.nlm.nih.gov/pubmed/22557585
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author Sharma, J. D.
Jha, R. K.
Gupta, Ira
Jain, Prabha
Dixit, V.P.
author_facet Sharma, J. D.
Jha, R. K.
Gupta, Ira
Jain, Prabha
Dixit, V.P.
author_sort Sharma, J. D.
collection PubMed
description Azadirachta indica (Neem) seed oil brings about a significant diminution in spermatozoan motility and density. It leads to reduction of fertility rate in rats and rabbits. The body weight of the animals remain unaffected but the weights of reproductive oranges declined. Reduction of cauda epididymal protein, sialic acid, acid phosphatase and seminal vesicular fructose concentration in rats and rabbits could bedue to antiandrogenic action of the seed oil as confirmed with the help of bioassay techniques. Histopathology of testis revealed arrest of spermatogenesis and sever degenerative changes in the cauda epididymis.
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spelling pubmed-33313772012-04-27 ‘ANTIANDROGENIC PROPERTIES OF NEEM SEED OIL (AZADIRACHTA INDICA) IN MALE RAT AND RABBI’ Sharma, J. D. Jha, R. K. Gupta, Ira Jain, Prabha Dixit, V.P. Anc Sci Life Original Article Azadirachta indica (Neem) seed oil brings about a significant diminution in spermatozoan motility and density. It leads to reduction of fertility rate in rats and rabbits. The body weight of the animals remain unaffected but the weights of reproductive oranges declined. Reduction of cauda epididymal protein, sialic acid, acid phosphatase and seminal vesicular fructose concentration in rats and rabbits could bedue to antiandrogenic action of the seed oil as confirmed with the help of bioassay techniques. Histopathology of testis revealed arrest of spermatogenesis and sever degenerative changes in the cauda epididymis. Medknow Publications & Media Pvt Ltd 1987 /pmc/articles/PMC3331377/ /pubmed/22557585 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Sharma, J. D.
Jha, R. K.
Gupta, Ira
Jain, Prabha
Dixit, V.P.
‘ANTIANDROGENIC PROPERTIES OF NEEM SEED OIL (AZADIRACHTA INDICA) IN MALE RAT AND RABBI’
title ‘ANTIANDROGENIC PROPERTIES OF NEEM SEED OIL (AZADIRACHTA INDICA) IN MALE RAT AND RABBI’
title_full ‘ANTIANDROGENIC PROPERTIES OF NEEM SEED OIL (AZADIRACHTA INDICA) IN MALE RAT AND RABBI’
title_fullStr ‘ANTIANDROGENIC PROPERTIES OF NEEM SEED OIL (AZADIRACHTA INDICA) IN MALE RAT AND RABBI’
title_full_unstemmed ‘ANTIANDROGENIC PROPERTIES OF NEEM SEED OIL (AZADIRACHTA INDICA) IN MALE RAT AND RABBI’
title_short ‘ANTIANDROGENIC PROPERTIES OF NEEM SEED OIL (AZADIRACHTA INDICA) IN MALE RAT AND RABBI’
title_sort ‘antiandrogenic properties of neem seed oil (azadirachta indica) in male rat and rabbi’
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331377/
https://www.ncbi.nlm.nih.gov/pubmed/22557585
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