ANTI – DIABETIC ACTIVITY OF THE SEED KERNEL OF SYZYGIUM CUMINI LINN

Syzygium cumini seed kernel (aqueous suspension) was screened for its antibiadetic activity at the dose levels of 1g., 2g., 4g and 6 g/kg body weight. 4g / kg dose level was found to exhibit maximum hypoglycaemic effect (42.64%) in rabbits, 3hr. after medication. Like Tolbutamide the drug may also b...

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Detalles Bibliográficos
Autores principales: Nair, R. Bhaskaran, Santhakumari, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 1986
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331408/
https://www.ncbi.nlm.nih.gov/pubmed/22557552
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author Nair, R. Bhaskaran
Santhakumari, G.
author_facet Nair, R. Bhaskaran
Santhakumari, G.
author_sort Nair, R. Bhaskaran
collection PubMed
description Syzygium cumini seed kernel (aqueous suspension) was screened for its antibiadetic activity at the dose levels of 1g., 2g., 4g and 6 g/kg body weight. 4g / kg dose level was found to exhibit maximum hypoglycaemic effect (42.64%) in rabbits, 3hr. after medication. Like Tolbutamide the drug may also be promoting endogenous release of insulin. An extra pancreatic site of action of the drug cannot be ruled out, since it produced a significant decrease in the blood sugar level (17.04%) in alloxan diabetic rats.
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spelling pubmed-33314082012-04-27 ANTI – DIABETIC ACTIVITY OF THE SEED KERNEL OF SYZYGIUM CUMINI LINN Nair, R. Bhaskaran Santhakumari, G. Anc Sci Life Original Article Syzygium cumini seed kernel (aqueous suspension) was screened for its antibiadetic activity at the dose levels of 1g., 2g., 4g and 6 g/kg body weight. 4g / kg dose level was found to exhibit maximum hypoglycaemic effect (42.64%) in rabbits, 3hr. after medication. Like Tolbutamide the drug may also be promoting endogenous release of insulin. An extra pancreatic site of action of the drug cannot be ruled out, since it produced a significant decrease in the blood sugar level (17.04%) in alloxan diabetic rats. Medknow Publications & Media Pvt Ltd 1986 /pmc/articles/PMC3331408/ /pubmed/22557552 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Nair, R. Bhaskaran
Santhakumari, G.
ANTI – DIABETIC ACTIVITY OF THE SEED KERNEL OF SYZYGIUM CUMINI LINN
title ANTI – DIABETIC ACTIVITY OF THE SEED KERNEL OF SYZYGIUM CUMINI LINN
title_full ANTI – DIABETIC ACTIVITY OF THE SEED KERNEL OF SYZYGIUM CUMINI LINN
title_fullStr ANTI – DIABETIC ACTIVITY OF THE SEED KERNEL OF SYZYGIUM CUMINI LINN
title_full_unstemmed ANTI – DIABETIC ACTIVITY OF THE SEED KERNEL OF SYZYGIUM CUMINI LINN
title_short ANTI – DIABETIC ACTIVITY OF THE SEED KERNEL OF SYZYGIUM CUMINI LINN
title_sort anti – diabetic activity of the seed kernel of syzygium cumini linn
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331408/
https://www.ncbi.nlm.nih.gov/pubmed/22557552
work_keys_str_mv AT nairrbhaskaran antidiabeticactivityoftheseedkernelofsyzygiumcuminilinn
AT santhakumarig antidiabeticactivityoftheseedkernelofsyzygiumcuminilinn

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