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RESPONSE OF COMMIPHORA MUKUL (GUGGULU) ON MELATONIN INDUCED HYPOTHYROIDISM
The results of this study indicate that melatonin induces hypothyroidism in mice within eight days. Simultaneous administration of melatonin and petroleum ether extract of Commiphora mukul brings about a significant improvement in thyroid structure and function. Further, melatonin induced hypothyroi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
1983
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331544/ https://www.ncbi.nlm.nih.gov/pubmed/22557386 |
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author | Singh, A. K. Tripathi, S. N. Prasad, G. C. |
author_facet | Singh, A. K. Tripathi, S. N. Prasad, G. C. |
author_sort | Singh, A. K. |
collection | PubMed |
description | The results of this study indicate that melatonin induces hypothyroidism in mice within eight days. Simultaneous administration of melatonin and petroleum ether extract of Commiphora mukul brings about a significant improvement in thyroid structure and function. Further, melatonin induced hypothyroidism is although a little reversible yet it is normalized quickly after C. mukul treatment. These data suggest that C. mukul directly stimulates thyroid function probably through some enzymatic mechanisms. |
format | Online Article Text |
id | pubmed-3331544 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1983 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-33315442012-04-27 RESPONSE OF COMMIPHORA MUKUL (GUGGULU) ON MELATONIN INDUCED HYPOTHYROIDISM Singh, A. K. Tripathi, S. N. Prasad, G. C. Anc Sci Life Original Article The results of this study indicate that melatonin induces hypothyroidism in mice within eight days. Simultaneous administration of melatonin and petroleum ether extract of Commiphora mukul brings about a significant improvement in thyroid structure and function. Further, melatonin induced hypothyroidism is although a little reversible yet it is normalized quickly after C. mukul treatment. These data suggest that C. mukul directly stimulates thyroid function probably through some enzymatic mechanisms. Medknow Publications & Media Pvt Ltd 1983 /pmc/articles/PMC3331544/ /pubmed/22557386 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Singh, A. K. Tripathi, S. N. Prasad, G. C. RESPONSE OF COMMIPHORA MUKUL (GUGGULU) ON MELATONIN INDUCED HYPOTHYROIDISM |
title | RESPONSE OF COMMIPHORA MUKUL (GUGGULU) ON MELATONIN INDUCED HYPOTHYROIDISM |
title_full | RESPONSE OF COMMIPHORA MUKUL (GUGGULU) ON MELATONIN INDUCED HYPOTHYROIDISM |
title_fullStr | RESPONSE OF COMMIPHORA MUKUL (GUGGULU) ON MELATONIN INDUCED HYPOTHYROIDISM |
title_full_unstemmed | RESPONSE OF COMMIPHORA MUKUL (GUGGULU) ON MELATONIN INDUCED HYPOTHYROIDISM |
title_short | RESPONSE OF COMMIPHORA MUKUL (GUGGULU) ON MELATONIN INDUCED HYPOTHYROIDISM |
title_sort | response of commiphora mukul (guggulu) on melatonin induced hypothyroidism |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331544/ https://www.ncbi.nlm.nih.gov/pubmed/22557386 |
work_keys_str_mv | AT singhak responseofcommiphoramukulgugguluonmelatonininducedhypothyroidism AT tripathisn responseofcommiphoramukulgugguluonmelatonininducedhypothyroidism AT prasadgc responseofcommiphoramukulgugguluonmelatonininducedhypothyroidism |