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Transgenerational Glucose Intolerance With Igf2/H19 Epigenetic Alterations in Mouse Islet Induced by Intrauterine Hyperglycemia
Gestational diabetes mellitus (GDM) has been shown to be associated with high risk of diabetes in offspring. However, the mechanisms involved and the possibilities of transgenerational transmission are still unclear. We intercrossed male and female adult control and first-generation offspring of GDM...
Autores principales: | Ding, Guo-Lian, Wang, Fang-Fang, Shu, Jing, Tian, Shen, Jiang, Ying, Zhang, Dan, Wang, Ning, Luo, Qiong, Zhang, Yu, Jin, Fan, Leung, Peter C.K., Sheng, Jian-Zhong, Huang, He-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331740/ https://www.ncbi.nlm.nih.gov/pubmed/22447856 http://dx.doi.org/10.2337/db11-1314 |
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