Calorie Restriction Reduces the Influence of Glucoregulatory Dysfunction on Regional Brain Volume in Aged Rhesus Monkeys

Insulin signaling dysregulation is related to neural atrophy in hippocampus and other areas affected by neurovascular and neurodegenerative disorders. It is not known if long-term calorie restriction (CR) can ameliorate this relationship through improved insulin signaling or if such an effect might...

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Detalles Bibliográficos
Autores principales: Willette, Auriel A., Bendlin, Barbara B., Colman, Ricki J., Kastman, Erik K., Field, Aaron S., Alexander, Andrew L., Sridharan, Aadhavi, Allison, David B., Anderson, Rozalyn, Voytko, Mary-Lou, Kemnitz, Joseph W., Weindruch, Richard H., Johnson, Sterling C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331743/
https://www.ncbi.nlm.nih.gov/pubmed/22415875
http://dx.doi.org/10.2337/db11-1187

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