Loss of AMP-Activated Protein Kinase-α2 Impairs the Insulin-Sensitizing Effect of Calorie Restriction in Skeletal Muscle

Whether the well-known metabolic switch AMP-activated protein kinase (AMPK) is involved in the insulin-sensitizing effect of calorie restriction (CR) is unclear. In this study, we investigated the role of AMPK in the insulin-sensitizing effect of CR in skeletal muscle. Wild-type (WT) and AMPK-α2(−/−...

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Detalles Bibliográficos
Autores principales: Wang, Pei, Zhang, Ruo-Yu, Song, Jie, Guan, Yun-Feng, Xu, Tian-Ying, Du, Hui, Viollet, Benoit, Miao, Chao-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331748/
https://www.ncbi.nlm.nih.gov/pubmed/22396207
http://dx.doi.org/10.2337/db11-1180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331748/
https://www.ncbi.nlm.nih.gov/pubmed/22396207
http://dx.doi.org/10.2337/db11-1180

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