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Diabetes-Associated Common Genetic Variation and Its Association With GLP-1 Concentrations and Response to Exogenous GLP-1
The mechanisms by which common genetic variation predisposes to type 2 diabetes remain unclear. The disease-associated variants in TCF7L2 (rs7903146) and WFS1 (rs10010131) have been shown to affect response to exogenous glucagon-like peptide 1 (GLP-1), while variants in KCNQ1 (rs151290, rs2237892, a...
Main Authors: | , , , , , , , |
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Format: | Online Article Text |
Language: | English |
Published: |
American Diabetes Association
2012
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Subjects: | |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331759/ https://www.ncbi.nlm.nih.gov/pubmed/22461567 http://dx.doi.org/10.2337/db11-1732 |