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Concordance of Changes in Metabolic Pathways Based on Plasma Metabolomics and Skeletal Muscle Transcriptomics in Type 1 Diabetes
Insulin regulates many cellular processes, but the full impact of insulin deficiency on cellular functions remains to be defined. Applying a mass spectrometry–based nontargeted metabolomics approach, we report here alterations of 330 plasma metabolites representing 33 metabolic pathways during an 8-...
Autores principales: | Dutta, Tumpa, Chai, High Seng, Ward, Lawrence E., Ghosh, Aditya, Persson, Xuan-Mai T., Ford, G. Charles, Kudva, Yogish C., Sun, Zhifu, Asmann, Yan W., Kocher, Jean-Pierre A., Nair, K. Sreekumaran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331761/ https://www.ncbi.nlm.nih.gov/pubmed/22415876 http://dx.doi.org/10.2337/db11-0874 |
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