Genetic variants of p27 and p21 as predictors for risk of second primary malignancy in patients with index squamous cell carcinoma of head and neck

BACKGROUND: Cell cycle deregulation is common in human cancer, and alterations of p27 and p21, two critical cell cycle regulators, have been implicated in the development of many human malignancies. Therefore, we hypothesize that p27 T109G polymorphism individually or in combination with p21 (C98A a...

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Detalles Bibliográficos
Autores principales: Wang, Zhongqiu, Sturgis, Erich M, Zhang, Fenghua, Lei, Dapeng, Liu, Zhensheng, Xu, Li, Song, Xicheng, Wei, Qingyi, Li, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331801/
https://www.ncbi.nlm.nih.gov/pubmed/22449259
http://dx.doi.org/10.1186/1476-4598-11-17

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