Cellulitis with Leukocytopenia as an Initial Sign of Acute Promyelocytic Leukemia

Patients with hematologic malignancies are immunosuppressive and may develop cutaneous or invasive infections as a primary sign of immune suppression. Acute promyelocytic leukemia (acute myeloid leukemia M3) is caused by translocation of reciprocal chromosomal rearrangement t(15;17), which produces...

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Autores principales: Sakamoto, Sachiko, Oiso, Naoki, Emoto, Masakatsu, Uchida, Shusuke, Hirao, Ayaka, Tatsumi, Yoichi, Matsumura, Itaru, Kawada, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Published: March, 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331878/
https://www.ncbi.nlm.nih.gov/pubmed/22529802
http://dx.doi.org/10.1159/000337195
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author Sakamoto, Sachiko
Oiso, Naoki
Emoto, Masakatsu
Uchida, Shusuke
Hirao, Ayaka
Tatsumi, Yoichi
Matsumura, Itaru
Kawada, Akira
author_facet Sakamoto, Sachiko
Oiso, Naoki
Emoto, Masakatsu
Uchida, Shusuke
Hirao, Ayaka
Tatsumi, Yoichi
Matsumura, Itaru
Kawada, Akira
author_sort Sakamoto, Sachiko
collection PubMed
description Patients with hematologic malignancies are immunosuppressive and may develop cutaneous or invasive infections as a primary sign of immune suppression. Acute promyelocytic leukemia (acute myeloid leukemia M3) is caused by translocation of reciprocal chromosomal rearrangement t(15;17), which produces an oncogenic protein. We herein describe a 71-year-old man having cellulitis with leukocytopenia as a first sign of acute promyelocytic leukemia. Dermatologists and hematologists should keep in mind that patients with a hematologic malignancy, such as acute promyelocytic leukemia, can develop cellulitis with leukocytopenia.
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spelling pubmed-33318782012-04-23 Cellulitis with Leukocytopenia as an Initial Sign of Acute Promyelocytic Leukemia Sakamoto, Sachiko Oiso, Naoki Emoto, Masakatsu Uchida, Shusuke Hirao, Ayaka Tatsumi, Yoichi Matsumura, Itaru Kawada, Akira Case Rep Dermatol Published: March, 2012 Patients with hematologic malignancies are immunosuppressive and may develop cutaneous or invasive infections as a primary sign of immune suppression. Acute promyelocytic leukemia (acute myeloid leukemia M3) is caused by translocation of reciprocal chromosomal rearrangement t(15;17), which produces an oncogenic protein. We herein describe a 71-year-old man having cellulitis with leukocytopenia as a first sign of acute promyelocytic leukemia. Dermatologists and hematologists should keep in mind that patients with a hematologic malignancy, such as acute promyelocytic leukemia, can develop cellulitis with leukocytopenia. S. Karger AG 2012-03-01 /pmc/articles/PMC3331878/ /pubmed/22529802 http://dx.doi.org/10.1159/000337195 Text en Copyright © 2012 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published: March, 2012
Sakamoto, Sachiko
Oiso, Naoki
Emoto, Masakatsu
Uchida, Shusuke
Hirao, Ayaka
Tatsumi, Yoichi
Matsumura, Itaru
Kawada, Akira
Cellulitis with Leukocytopenia as an Initial Sign of Acute Promyelocytic Leukemia
title Cellulitis with Leukocytopenia as an Initial Sign of Acute Promyelocytic Leukemia
title_full Cellulitis with Leukocytopenia as an Initial Sign of Acute Promyelocytic Leukemia
title_fullStr Cellulitis with Leukocytopenia as an Initial Sign of Acute Promyelocytic Leukemia
title_full_unstemmed Cellulitis with Leukocytopenia as an Initial Sign of Acute Promyelocytic Leukemia
title_short Cellulitis with Leukocytopenia as an Initial Sign of Acute Promyelocytic Leukemia
title_sort cellulitis with leukocytopenia as an initial sign of acute promyelocytic leukemia
topic Published: March, 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331878/
https://www.ncbi.nlm.nih.gov/pubmed/22529802
http://dx.doi.org/10.1159/000337195
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