Reactivation of Tuberculosis in Three Cases of Psoriasis after Initiation of Anti-TNF Therapy

New biological therapies for disabling diseases such as psoriasis may carry both short- and long-term risks. Tuberculosis (TB) reactivation is a frequent complication of anti-tumor necrosis factor (TNF) therapy. We present 3 cases of psoriasis that were treated with different types of anti-TNF and d...

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Detalles Bibliográficos
Autores principales: Shaikha, Samya Abu, Mansour, Khalid, Riad, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Published: February, 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331879/
https://www.ncbi.nlm.nih.gov/pubmed/22529801
http://dx.doi.org/10.1159/000337145
Descripción
Sumario:New biological therapies for disabling diseases such as psoriasis may carry both short- and long-term risks. Tuberculosis (TB) reactivation is a frequent complication of anti-tumor necrosis factor (TNF) therapy. We present 3 cases of psoriasis that were treated with different types of anti-TNF and developed TB infection (TBI) during therapy. One of the cases was diagnosed as active pulmonary TB and the other 2 cases as latent TBI. All cases received appropriate anti-TB treatment, and the anti-TNF therapy was interrupted and then resumed according to various clinical considerations.

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