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Reactivation of Tuberculosis in Three Cases of Psoriasis after Initiation of Anti-TNF Therapy

New biological therapies for disabling diseases such as psoriasis may carry both short- and long-term risks. Tuberculosis (TB) reactivation is a frequent complication of anti-tumor necrosis factor (TNF) therapy. We present 3 cases of psoriasis that were treated with different types of anti-TNF and d...

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Autores principales: Shaikha, Samya Abu, Mansour, Khalid, Riad, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331879/
https://www.ncbi.nlm.nih.gov/pubmed/22529801
http://dx.doi.org/10.1159/000337145
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author Shaikha, Samya Abu
Mansour, Khalid
Riad, Hassan
author_facet Shaikha, Samya Abu
Mansour, Khalid
Riad, Hassan
author_sort Shaikha, Samya Abu
collection PubMed
description New biological therapies for disabling diseases such as psoriasis may carry both short- and long-term risks. Tuberculosis (TB) reactivation is a frequent complication of anti-tumor necrosis factor (TNF) therapy. We present 3 cases of psoriasis that were treated with different types of anti-TNF and developed TB infection (TBI) during therapy. One of the cases was diagnosed as active pulmonary TB and the other 2 cases as latent TBI. All cases received appropriate anti-TB treatment, and the anti-TNF therapy was interrupted and then resumed according to various clinical considerations.
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spelling pubmed-33318792012-04-23 Reactivation of Tuberculosis in Three Cases of Psoriasis after Initiation of Anti-TNF Therapy Shaikha, Samya Abu Mansour, Khalid Riad, Hassan Case Rep Dermatol Published: February, 2012 New biological therapies for disabling diseases such as psoriasis may carry both short- and long-term risks. Tuberculosis (TB) reactivation is a frequent complication of anti-tumor necrosis factor (TNF) therapy. We present 3 cases of psoriasis that were treated with different types of anti-TNF and developed TB infection (TBI) during therapy. One of the cases was diagnosed as active pulmonary TB and the other 2 cases as latent TBI. All cases received appropriate anti-TB treatment, and the anti-TNF therapy was interrupted and then resumed according to various clinical considerations. S. Karger AG 2012-02-25 /pmc/articles/PMC3331879/ /pubmed/22529801 http://dx.doi.org/10.1159/000337145 Text en Copyright © 2012 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published: February, 2012
Shaikha, Samya Abu
Mansour, Khalid
Riad, Hassan
Reactivation of Tuberculosis in Three Cases of Psoriasis after Initiation of Anti-TNF Therapy
title Reactivation of Tuberculosis in Three Cases of Psoriasis after Initiation of Anti-TNF Therapy
title_full Reactivation of Tuberculosis in Three Cases of Psoriasis after Initiation of Anti-TNF Therapy
title_fullStr Reactivation of Tuberculosis in Three Cases of Psoriasis after Initiation of Anti-TNF Therapy
title_full_unstemmed Reactivation of Tuberculosis in Three Cases of Psoriasis after Initiation of Anti-TNF Therapy
title_short Reactivation of Tuberculosis in Three Cases of Psoriasis after Initiation of Anti-TNF Therapy
title_sort reactivation of tuberculosis in three cases of psoriasis after initiation of anti-tnf therapy
topic Published: February, 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331879/
https://www.ncbi.nlm.nih.gov/pubmed/22529801
http://dx.doi.org/10.1159/000337145
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