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Resveratrol Prevents Endothelial Cells Injury in High-Dose Interleukin-2 Therapy against Melanoma

Immunotherapy with high-dose interleukin-2 (HDIL-2) is an effective treatment for patients with metastatic melanoma and renal cell carcinoma. However, it is accompanied by severe toxicity involving endothelial cell injury and induction of vascular leak syndrome (VLS). In this study, we found that re...

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Detalles Bibliográficos
Autores principales: Guan, Hongbing, Singh, Narendra P., Singh, Udai P., Nagarkatti, Prakash S., Nagarkatti, Mitzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331985/
https://www.ncbi.nlm.nih.gov/pubmed/22532866
http://dx.doi.org/10.1371/journal.pone.0035650