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pVHL Mediates K63-Linked Ubiquitination of nCLU

pVHL, product of von Hippel-Lindau (VHL) tumor suppressor gene, functions as the substrate recognition component of an E3-ubiquitin ligase that targets proteins for ubiquitination and proteasomal degradation. Hypoxia-inducible factor α (HIFα) is the well-known substrate of pVHL. Besides HIFα, pVHL a...

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Detalles Bibliográficos
Autores principales:	Xue, Jing, Lv, Dan-dan, Jiao, Shi, Zhao, Wenting, Li, Xuebing, Sun, Heng, Yan, Bing, Fan, Li, Hu, Rong-gui, Fang, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332038/ https://www.ncbi.nlm.nih.gov/pubmed/22532874 http://dx.doi.org/10.1371/journal.pone.0035848

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