Depletion of Trypanosome CTR9 Leads to Gene Expression Defects

The Paf complex of Opisthokonts and plants contains at least five subunits: Paf1, Cdc73, Rtf1, Ctr9, and Leo1. Mutations in, or loss of Paf complex subunits have been shown to cause defects in histone modification, mRNA polyadenylation, and transcription by RNA polymerase I and RNA polymerase II. We...

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Detalles Bibliográficos
Autores principales: Ouna, Benard A., Nyambega, Benson, Manful, Theresa, Helbig, Claudia, Males, Matilda, Fadda, Abeer, Clayton, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332058/
https://www.ncbi.nlm.nih.gov/pubmed/22532828
http://dx.doi.org/10.1371/journal.pone.0034256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332058/
https://www.ncbi.nlm.nih.gov/pubmed/22532828
http://dx.doi.org/10.1371/journal.pone.0034256

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