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Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase Modulates Oscillations of Pancreatic Islet Metabolism

Pulses of insulin from pancreatic beta-cells help maintain blood glucose in a narrow range, although the source of these pulses is unclear. It has been proposed that a positive feedback circuit exists within the glycolytic pathway, the autocatalytic activation of phosphofructokinase-1 (PFK1), which...

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Detalles Bibliográficos
Autores principales:	Merrins, Matthew J., Bertram, Richard, Sherman, Arthur, Satin, Leslie S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332096/ https://www.ncbi.nlm.nih.gov/pubmed/22532827 http://dx.doi.org/10.1371/journal.pone.0034036

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