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Effect of Ginkgo biloba special extract EGb 761® on human cytochrome P450 activity: a cocktail interaction study in healthy volunteers

PURPOSE: We assessed the human in vivo metabolic drug interaction profile of Ginkgo biloba extract EGb 761® with respect to the activities of major cytochrome P450 (CYP) enzymes. METHODS: A single-center, open-label, randomized, three-fold crossover, cocktail phenotyping design was applied. In rando...

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Detalles Bibliográficos
Autores principales: Zadoyan, G., Rokitta, D., Klement, S., Dienel, A., Hoerr, R., Gramatté, T., Fuhr, U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332346/
https://www.ncbi.nlm.nih.gov/pubmed/22189672
http://dx.doi.org/10.1007/s00228-011-1174-5