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High similarity of phylogenetic profiles of rate-limiting enzymes with inhibitory relation in Human, Mouse, Rat, budding Yeast and E. coli

BACKGROUND: The phylogenetic profile is widely used to characterize functional linkage and conservation between proteins without amino acid sequence similarity. To survey the conservative regulatory properties of rate-limiting enzymes (RLEs) in metabolic inhibitory network across different species,...

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Detalles Bibliográficos
Autores principales: Zhao, Min, Qu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333169/
https://www.ncbi.nlm.nih.gov/pubmed/22369203
http://dx.doi.org/10.1186/1471-2164-12-S3-S10