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Algorithms for optimizing cross-overs in DNA shuffling
BACKGROUND: DNA shuffling generates combinatorial libraries of chimeric genes by stochastically recombining parent genes. The resulting libraries are subjected to large-scale genetic selection or screening to identify those chimeras with favorable properties (e.g., enhanced stability or enzymatic ac...
Autores principales: | He, Lu, Friedman, Alan M, Bailey-Kellogg, Chris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333841/ https://www.ncbi.nlm.nih.gov/pubmed/22536901 http://dx.doi.org/10.1186/1471-2105-13-S3-S3 |
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