Cargando…

Type III restriction endonuclease EcoP15I is a heterotrimeric complex containing one Res subunit with several DNA-binding regions and ATPase activity

For efficient DNA cleavage, the Type III restriction endonuclease EcoP15I communicates with two inversely oriented recognition sites in an ATP-dependent process. EcoP15I consists of methylation (Mod) and restriction (Res) subunits forming a multifunctional enzyme complex able to methylate or to clea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wyszomirski, Karol H., Curth, Ute, Alves, Jürgen, Mackeldanz, Petra, Möncke-Buchner, Elisabeth, Schutkowski, Mike, Krüger, Detlev H., Reuter, Monika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333885/ https://www.ncbi.nlm.nih.gov/pubmed/22199260 http://dx.doi.org/10.1093/nar/gkr1239

Ejemplares similares

Creating highly specific nucleases by fusion of active restriction endonucleases and catalytically inactive homing endonucleases
por: Fonfara, Ines, et al.
Publicado: (2012)

Type III restriction endonucleases are heterotrimeric: comprising one helicase–nuclease subunit and a dimeric methyltransferase that binds only one specific DNA
por: Butterer, Annika, et al.
Publicado: (2014)

A RecB-family nuclease motif in the Type I restriction endonuclease EcoR124I
por: Šišáková, Eva, et al.
Publicado: (2008)

S-Adenosyl homocysteine and DNA ends stimulate promiscuous nuclease activities in the Type III restriction endonuclease EcoPI
por: Peakman, Luke J., et al.
Publicado: (2009)

Natural zinc ribbon HNH endonucleases and engineered zinc finger nicking endonuclease
por: Xu, Shuang-yong, et al.
Publicado: (2013)

Single-site DNA cleavage by Type III restriction endonuclease requires a site-bound enzyme and a trans-acting enzyme that are ATPase-activated
por: Ahmad, Ishtiyaq, et al.
Publicado: (2018)

Endonuclease domain of non-LTR retrotransposons: loss-of-function mutants and modeling of the R2Bm endonuclease
por: Govindaraju, Aruna, et al.
Publicado: (2016)

Catalytic domain of restriction endonuclease BmrI as a cleavage module for engineering endonucleases with novel substrate specificities
por: Chan, Siu-hong, et al.
Publicado: (2007)

Thermodynamics of DNA target site recognition by homing endonucleases
por: Eastberg, Jennifer H., et al.
Publicado: (2007)

Type I restriction endonucleases are true catalytic enzymes
por: Bianco, Piero R., et al.
Publicado: (2009)

Characterization of the 5-hydroxymethylcytosine-specific DNA restriction endonucleases
por: Borgaro, Janine G., et al.
Publicado: (2013)

Massively parallel determination and modeling of endonuclease substrate specificity
por: Thyme, Summer B., et al.
Publicado: (2014)

In vivo cleavage specificity of Trypanosoma brucei editosome endonucleases
por: Carnes, Jason, et al.
Publicado: (2017)

Restriction glycosylases: involvement of endonuclease activities in the restriction process
por: Zhang, Yingbiao, et al.
Publicado: (2017)

EXOG, a novel paralog of Endonuclease G in higher eukaryotes
por: Cymerman, Iwona A., et al.
Publicado: (2008)

Dynamics and consequences of DNA looping by the FokI restriction endonuclease
por: Catto, Lucy E., et al.
Publicado: (2008)

Increasing cleavage specificity and activity of restriction endonuclease KpnI
por: Vasu, Kommireddy, et al.
Publicado: (2013)

Concerted action at eight phosphodiester bonds by the BcgI restriction endonuclease
por: Marshall, Jacqueline J. T., et al.
Publicado: (2011)

Pso2 (SNM1) is a DNA structure-specific endonuclease
por: Tiefenbach, Tracy, et al.
Publicado: (2012)

Rational engineering of sequence specificity in R.MwoI restriction endonuclease
por: Skowronek, Krzysztof, et al.
Publicado: (2012)

A unique family of Mrr-like modification-dependent restriction endonucleases
por: Zheng, Yu, et al.
Publicado: (2010)

The Type II restriction endonuclease MvaI has dual specificity
por: Stier, Ildikó, et al.
Publicado: (2010)

Cleavage of adenine-modified functionalized DNA by type II restriction endonucleases
por: Macíčková-Cahová, Hana, et al.
Publicado: (2009)

Substrate specificity of the MUS81-EME2 structure selective endonuclease
por: Pepe, Alessandra, et al.
Publicado: (2014)

Observation of unpaired substrate DNA in the flap endonuclease-1 active site
por: David Finger, L., et al.
Publicado: (2013)

Reprogramming homing endonuclease specificity through computational design and directed evolution
por: Thyme, Summer B., et al.
Publicado: (2014)

A protein architecture guided screen for modification dependent restriction endonucleases
por: Lutz, Thomas, et al.
Publicado: (2019)

A nucleotide-sensing endonuclease from the Gabija bacterial defense system
por: Cheng, Rui, et al.
Publicado: (2021)

Structures, activity and mechanism of the Type IIS restriction endonuclease PaqCI
por: Kennedy, Madison A, et al.
Publicado: (2023)

The rotation-coupled sliding of EcoRV
por: Dikić, Jasmina, et al.
Publicado: (2012)

Homing endonuclease I-CreI derivatives with novel DNA target specificities
por: Rosen, Laura E., et al.
Publicado: (2006)

Native homing endonucleases can target conserved genes in humans and in animal models
por: Barzel, Adi, et al.
Publicado: (2011)

Creation of a type IIS restriction endonuclease with a long recognition sequence
por: Lippow, Shaun M., et al.
Publicado: (2009)

Targeting individual subunits of the FokI restriction endonuclease to specific DNA strands
por: Sanders, Kelly L., et al.
Publicado: (2009)

Crystal structure and assembly of the functional Nanoarchaeum equitans tRNA splicing endonuclease
por: Mitchell, Michelle, et al.
Publicado: (2009)

Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease
por: Grizot, Sylvestre, et al.
Publicado: (2009)

Expanding LAGLIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence space
por: Jacoby, Kyle, et al.
Publicado: (2012)

Structural mechanisms of the degenerate sequence recognition by Bse634I restriction endonuclease
por: Manakova, Elena, et al.
Publicado: (2012)

Rational engineering of type II restriction endonuclease DNA binding and cleavage specificity
por: Morgan, Richard D., et al.
Publicado: (2009)

Cellular localization and dynamics of the Mrr type IV restriction endonuclease of Escherichia coli
por: Ghosh, Anirban, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_mp5pqm3rupmqjhmlk0jrgsv92u