Cargando…
A potent 2′-O-methylated RNA-based microRNA inhibitor with unique secondary structures
MicroRNAs (miRNAs) are involved in various biological processes and human diseases. The development of strong low-molecular weight inhibitors of specific miRNAs is thus expected to be useful in providing tools for basic research or in generating promising new therapeutic drugs. We have previously de...
Autores principales: | Haraguchi, Takeshi, Nakano, Haruo, Tagawa, Takanobu, Ohki, Tokimitsu, Ueno, Yoshihito, Yoshida, Tetsuo, Iba, Hideo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333889/ https://www.ncbi.nlm.nih.gov/pubmed/22259037 http://dx.doi.org/10.1093/nar/gkr1317 |
Ejemplares similares
-
Vectors expressing efficient RNA decoys achieve the long-term suppression of specific microRNA activity in mammalian cells
por: Haraguchi, Takeshi, et al.
Publicado: (2009) -
Integrated analysis of microRNA and mRNA expression: adding biological significance to microRNA target predictions
por: van Iterson, Maarten, et al.
Publicado: (2013) -
The microRNA body map: dissecting microRNA function through integrative genomics
por: Mestdagh, Pieter, et al.
Publicado: (2011) -
A single anti-microRNA antisense oligodeoxyribonucleotide (AMO) targeting multiple microRNAs offers an improved approach for microRNA interference
por: Lu, Yanjie, et al.
Publicado: (2009) -
Identification of microRNAs with regulatory potential using a matched microRNA-mRNA time-course data
por: Jayaswal, Vivek, et al.
Publicado: (2009)