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Connecting LKB1 and AMPK links metabolism with cancer

The tumor suppressor gene product LKB1 has been identified as the upstream activating kinase for the stress-responsive AMP-activated kinase, providing a link between regulators of cellular metabolism and cell proliferation in cancer.

Detalles Bibliográficos
Autor principal: Moore, Pete
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC333406/
http://dx.doi.org/10.1186/1475-4924-2-24
Descripción
Sumario:The tumor suppressor gene product LKB1 has been identified as the upstream activating kinase for the stress-responsive AMP-activated kinase, providing a link between regulators of cellular metabolism and cell proliferation in cancer.