At the crossroads: AMP-activated kinase and the LKB1 tumor suppressor link cell proliferation to metabolic regulation

The tumor suppressor kinase LKB1 has been identified as a physiologic activator of the key metabolic regulator 5'-AMP-activated protein kinase, establishing a possible molecular link between the regulation of metabolism and cell proliferation.

Detalles Bibliográficos
Autor principal: Kyriakis, John M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC333408/
https://www.ncbi.nlm.nih.gov/pubmed/14575531
http://dx.doi.org/10.1186/1475-4924-2-26
Descripción
Sumario:The tumor suppressor kinase LKB1 has been identified as a physiologic activator of the key metabolic regulator 5'-AMP-activated protein kinase, establishing a possible molecular link between the regulation of metabolism and cell proliferation.

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