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At the crossroads: AMP-activated kinase and the LKB1 tumor suppressor link cell proliferation to metabolic regulation
The tumor suppressor kinase LKB1 has been identified as a physiologic activator of the key metabolic regulator 5'-AMP-activated protein kinase, establishing a possible molecular link between the regulation of metabolism and cell proliferation.
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2003
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC333408/ https://www.ncbi.nlm.nih.gov/pubmed/14575531 http://dx.doi.org/10.1186/1475-4924-2-26 |
| _version_ | 1782121207261298688 |
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| author | Kyriakis, John M |
| author_facet | Kyriakis, John M |
| author_sort | Kyriakis, John M |
| collection | PubMed |
| description | The tumor suppressor kinase LKB1 has been identified as a physiologic activator of the key metabolic regulator 5'-AMP-activated protein kinase, establishing a possible molecular link between the regulation of metabolism and cell proliferation. |
| format | Text |
| id | pubmed-333408 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2003 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-3334082004-02-07 At the crossroads: AMP-activated kinase and the LKB1 tumor suppressor link cell proliferation to metabolic regulation Kyriakis, John M J Biol Minireview The tumor suppressor kinase LKB1 has been identified as a physiologic activator of the key metabolic regulator 5'-AMP-activated protein kinase, establishing a possible molecular link between the regulation of metabolism and cell proliferation. BioMed Central 2003 2003-10-22 /pmc/articles/PMC333408/ /pubmed/14575531 http://dx.doi.org/10.1186/1475-4924-2-26 Text en Copyright © 2003 BioMed Central Ltd |
| spellingShingle | Minireview Kyriakis, John M At the crossroads: AMP-activated kinase and the LKB1 tumor suppressor link cell proliferation to metabolic regulation |
| title | At the crossroads: AMP-activated kinase and the LKB1 tumor suppressor link cell proliferation to metabolic regulation |
| title_full | At the crossroads: AMP-activated kinase and the LKB1 tumor suppressor link cell proliferation to metabolic regulation |
| title_fullStr | At the crossroads: AMP-activated kinase and the LKB1 tumor suppressor link cell proliferation to metabolic regulation |
| title_full_unstemmed | At the crossroads: AMP-activated kinase and the LKB1 tumor suppressor link cell proliferation to metabolic regulation |
| title_short | At the crossroads: AMP-activated kinase and the LKB1 tumor suppressor link cell proliferation to metabolic regulation |
| title_sort | at the crossroads: amp-activated kinase and the lkb1 tumor suppressor link cell proliferation to metabolic regulation |
| topic | Minireview |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC333408/ https://www.ncbi.nlm.nih.gov/pubmed/14575531 http://dx.doi.org/10.1186/1475-4924-2-26 |
| work_keys_str_mv | AT kyriakisjohnm atthecrossroadsampactivatedkinaseandthelkb1tumorsuppressorlinkcellproliferationtometabolicregulation |