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Diffuse unilateral subacute neuroretinitis in a young boy: a case report

We report a case of diffuse unilateral subacute neuroretinitis in a young boy with no clinical visualization of nematode. The diagnosis was made based on clinical findings and detection of Toxocara immunoglobulin G by Western blot test. An 11-year-old Malay boy presented with progressive blurring of...

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Autores principales: Guan-Fook, Ng, Hayati, Abd Aziz, Raja-Azmi, Mohd Noor, Liza-Sharmini, Ahmad Tajudin, Wan-Hazabbah, Wan Hitam, Zunaina, Embong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334223/
https://www.ncbi.nlm.nih.gov/pubmed/22536041
http://dx.doi.org/10.2147/OPTH.S29806
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author Guan-Fook, Ng
Hayati, Abd Aziz
Raja-Azmi, Mohd Noor
Liza-Sharmini, Ahmad Tajudin
Wan-Hazabbah, Wan Hitam
Zunaina, Embong
author_facet Guan-Fook, Ng
Hayati, Abd Aziz
Raja-Azmi, Mohd Noor
Liza-Sharmini, Ahmad Tajudin
Wan-Hazabbah, Wan Hitam
Zunaina, Embong
author_sort Guan-Fook, Ng
collection PubMed
description We report a case of diffuse unilateral subacute neuroretinitis in a young boy with no clinical visualization of nematode. The diagnosis was made based on clinical findings and detection of Toxocara immunoglobulin G by Western blot test. An 11-year-old Malay boy presented with progressive blurring of vision in the left eye for a duration of 1 year. It was associated with intermittent floaters. Visual acuity in the left eye was 6/45 and improved to 6/24 with pinhole. There was positive relative afferent pupillary defect, impaired color vision, and presence of red desaturation in the left eye. There were occasional cells in the anterior chamber with no conjunctiva injection. Posterior segment examination revealed mild-to-moderate vitritis and generalized pigmentary changes of the retina with attenuated vessels. The optic disk was slightly hyperemic with mild edema. There was presence of multiple, focal, gray-white subretinal lesions at the inferior part of the retina. Full blood picture results showed eosinophilia with detection of Toxocara immunoglobulin G by Western blot test. Investigations for other infective causes and connective tissue diseases were negative. The diagnosis of diffuse unilateral subacute neuroretinitis secondary to Toxocara was made based on clinical findings and laboratory results. He was treated with oral albendazole 400 mg daily for 5 days and oral prednisolone 1 mg/kg with tapering doses over 6 weeks. At 1 month follow-up, the inflammation had reduced, and multiple, focal, gray-white subretinal lesions were resolved; however there was no improvement of vision.
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spelling pubmed-33342232012-04-25 Diffuse unilateral subacute neuroretinitis in a young boy: a case report Guan-Fook, Ng Hayati, Abd Aziz Raja-Azmi, Mohd Noor Liza-Sharmini, Ahmad Tajudin Wan-Hazabbah, Wan Hitam Zunaina, Embong Clin Ophthalmol Case Report We report a case of diffuse unilateral subacute neuroretinitis in a young boy with no clinical visualization of nematode. The diagnosis was made based on clinical findings and detection of Toxocara immunoglobulin G by Western blot test. An 11-year-old Malay boy presented with progressive blurring of vision in the left eye for a duration of 1 year. It was associated with intermittent floaters. Visual acuity in the left eye was 6/45 and improved to 6/24 with pinhole. There was positive relative afferent pupillary defect, impaired color vision, and presence of red desaturation in the left eye. There were occasional cells in the anterior chamber with no conjunctiva injection. Posterior segment examination revealed mild-to-moderate vitritis and generalized pigmentary changes of the retina with attenuated vessels. The optic disk was slightly hyperemic with mild edema. There was presence of multiple, focal, gray-white subretinal lesions at the inferior part of the retina. Full blood picture results showed eosinophilia with detection of Toxocara immunoglobulin G by Western blot test. Investigations for other infective causes and connective tissue diseases were negative. The diagnosis of diffuse unilateral subacute neuroretinitis secondary to Toxocara was made based on clinical findings and laboratory results. He was treated with oral albendazole 400 mg daily for 5 days and oral prednisolone 1 mg/kg with tapering doses over 6 weeks. At 1 month follow-up, the inflammation had reduced, and multiple, focal, gray-white subretinal lesions were resolved; however there was no improvement of vision. Dove Medical Press 2012 2012-03-27 /pmc/articles/PMC3334223/ /pubmed/22536041 http://dx.doi.org/10.2147/OPTH.S29806 Text en © 2012 Guan-Fook et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Case Report
Guan-Fook, Ng
Hayati, Abd Aziz
Raja-Azmi, Mohd Noor
Liza-Sharmini, Ahmad Tajudin
Wan-Hazabbah, Wan Hitam
Zunaina, Embong
Diffuse unilateral subacute neuroretinitis in a young boy: a case report
title Diffuse unilateral subacute neuroretinitis in a young boy: a case report
title_full Diffuse unilateral subacute neuroretinitis in a young boy: a case report
title_fullStr Diffuse unilateral subacute neuroretinitis in a young boy: a case report
title_full_unstemmed Diffuse unilateral subacute neuroretinitis in a young boy: a case report
title_short Diffuse unilateral subacute neuroretinitis in a young boy: a case report
title_sort diffuse unilateral subacute neuroretinitis in a young boy: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334223/
https://www.ncbi.nlm.nih.gov/pubmed/22536041
http://dx.doi.org/10.2147/OPTH.S29806
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